自体肾移植术治疗顽固性肾血管性高血压的临床价值（附5例报告）

李俊平; 潘敏杰; 张龙; 郭琛; 李恒; 王振迪; 蒋国松; 曾甫清

doi:10.13201/j.issn.1001-1420.2014.02.014

自体肾移植术治疗顽固性肾血管性高血压的临床价值（附5例报告）

- 1. 华中科技大学同济医学院附属协和医院泌尿外科(武汉, 430022);
- 2. 湖北省荆门市第一人民医院泌尿外科;
- 3. 江苏省常州市第二人民医院泌尿外科

详细信息

通讯作者: 王振迪, E-mail:wangzhendi@gmail.com

中图分类号: R692.16

收稿日期: 2013-08-15

Renal autotransplantation for treatment of intractable renovascular hypertension（Report of five cases）

- 1 Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China;
- 2 Department of Urology, First People's Hospital of Jingmen;
- 3 Department of Urology, Second People's Hospital of Changzhou

More Information

Corresponding author: WANG Zhendi, E-mail: wangzhendi@gmail.com

Received Date: 15 August 2013

摘要

摘要: 目的: 总结采取自体肾移植术(renal autotransplantation, RAT)治疗因重度肾动脉狭窄(renal artery stenosis, RAS)所致顽固性肾血管性高血压(intractable renal vascular hypertension, IRVH)的经验并探讨其临床应用价值。方法: 回顾性分析武汉协和医院收治5例IRVH患者的临床资料及随访结果,观察术后患者血压改善情况及移植肾功能状况,并复习相关文献。结果: 4例单侧重度RAS患者术后血压均降至正常范围,于术后20~35天停服降压药物。1例双侧RAS患者左侧行自体肾移植术后血压明显下降,出院后1个月右侧行经皮腔内肾动脉支架成形术(percutaneous transluminal renal artery stenting PTRAS),术后63天停服降压药物。随访6个月~3年,5例患者血压维持在正常范围,移植肾功能正常。结论: 针对于肾动脉重度狭窄的患者,当无法行PTRAS术时,RAT可作为首选的治疗方法,而且疗效确切。
- 自体肾移植 /
- 肾血管性高血压 /
- 肾动脉狭窄
Abstract: Objective: To summarize the experience of renal autotransplantation (RAT) for intractable renal vascular hypertension (IRVH) caused by severe renal artery stenosis (RAS) in five patients and to explore the clinical application value of RAT. Method:The clinical data and follow-up results of five patients undergoing RAT were reviewed retrospectively, then we observed postoperative blood pressure and graft function during the follow-up period, and reviewed related literatures. Result:Postoperative blood pressure of four patients with unilateral RAS dropped to normal range after RAT. They stopped taking antihypertensive drugs 20-35 days postoperatively. Postoperative blood pressure of a case of bilateral RAS decreased significantly after left RAT. Furthermore, percutaneous transluminal renal artery stenting (PTRAS) was applied to the right renal artery a month after RAT. In the end, antihypertensive drugs was stopped taking 63 days after the second operation. Blood pressure and graft function of all patients were maintained well during follow-up period of six months to three years. Conclusion: Renal autotransplantation (RAT) can be appropriate for patients with severe renal artery stenosis that couldn't be treated with PTRAS. It is a safe and successful procedure considering satisfying results.Key words renal autotransplantation; renal vascular hypertension; renal artery stenosis
- renal autotransplantation /
- renal vascular hypertension /
- renal artery stenosis

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参考文献(8)

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