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摘要: 原发性醛固酮增多症（primary aldosteronism，PA）是由于肾上腺皮质球状带功能紊乱导致的醛固酮分泌增加所引起的一类内分泌系统疾病。目前，PA已被公认为继发性高血压的最常见形式。PA患者体内过高的醛固酮水平可导致相应的靶器官损害，其严重心血管事件的发生率远高于原发性高血压患者。因此，对PA患者的早期发现和诊断、治疗尤为重要。本文就近年来PA的最新诊疗进展作一综述。Abstract: Primary aldosteronism (PA) is an endocrine system disease caused by increasing secretion of aldosterone in the adrenal zona glomerulosa (ZG). At present, PA is considered as the most common form of secondary hypertension. The high level of plasma aldosterone is associated with increased target organ damage and it had a higher incidence of cardiovascular events in comparison with primary hypertension. Therefore, early and correct detection, diagnosis and treatment is particularly important in patients with PA. This review briefly introduces latest progress in diagnosis and treatment of PA.
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Key words:
- primary aldosteronism /
- secondary hypertension /
- diagnosis /
- treatment
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