Advances in the role of matrix proteins in the formation of urinary stones and its mechanism
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摘要: 泌尿系结石是世界范围内最常见的泌尿系统疾病之一，是由多种因素共同作用下的良性疾病，然而其发病机制尚不明确。本文旨在对泌尿系结石中的蛋白质成分的研究进展作一综述，通过对目前结石基质蛋白（SMP）在不同成分结石的发生发展中的作用及可能机制的研究进行总结归纳，为后续深入的研究泌尿系结石的发病机制提供理论基础和研究方向。Abstract: Urolithiasis is one of the most common urological diseases in the world.It is a benign disease caused by multiple factors.However, its pathogenesis is still unclear.This article is aimed at making a review on the research progress of protein in urinary calculi.Then we summarize the research on the role and possible mechanism of the stone matrix proteins in the occurrence and development of different components of stones in order to provide a theoretical basis and research direction for the subsequent in-depth study of the pathogenesis of urinary calculi.
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Key words:
- urinary calculi /
- matrix proteins /
- proteomics
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