核磁共振成像对良性前列腺增生组织成分的预测研究

康健; 管雯斌; 朱自强; 李晓明; 周硕明; 徐丁; 段刘剑; 齐隽

doi:10.13201/j.issn.1001-1420.2020.05.008

核磁共振成像对良性前列腺增生组织成分的预测研究

- 1. 上海交通大学医学院附属新华医院泌尿外科(上海, 200092);
- 2. 上海交通大学医学院附属新华医院病理科;
- 3. 上海交通大学医学院附属新华医院放射科

详细信息

通讯作者: 康健,E-mail:kangjian01@xinhuamed.com.cn

中图分类号: R697

收稿日期: 2020-02-20

Predictive study on magnetic resonance imaging on tissue composition of benign prostatic hyperplasia

- 1. Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, 200092, China;
- 2. Department of Pathology, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine;
- 3. Department of Radiology, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine

More Information

Corresponding author: KANG Jian, E-mail: kangjian01@xinhuamed.com.cn

Received Date: 20 February 2020

摘要

摘要: 目的:研究核磁共振成像(MRI)与良性前列腺增生(BPH)组织学成分的关系。方法:选取43例前列腺穿刺患者(均确认为BPH),穿刺前行核磁共振检查。穿刺标本进行腺体百分比测算,并记录各穿刺点的影像学信号强度,进行差异性分析。利用IMAGE J软件对MRI图像进行分析,判断腺体成分比,并与前列腺体积(TPV)、前列腺特异性抗原(PSA)、国际前列腺症状评分(IPSS)、残余尿量(RUV)等临床数据进行相关性分析。结果:腺瘤组、混合组、间质组在穿刺点/外周带信号比上存在显著性差异,提示腺体成分表现出较高的信号比而间质成分信号比较低。影像学图片中腺体成分比与PSA、TPV存在正相关性,与IPSS评分和RUV无明显相关性。结论:通过MRI检查,可以在临床上通过无创的方法,来判断增生部分的腺体比例,为治疗用药和决策提供帮助。
- 核磁共振成像 /
- 良性前列腺增生 /
- 前列腺组织成分 /
- 前列腺穿刺活检
Abstract: Objective: To study the predictive value of magnetic resonance imaging(MRI) signal intensity on benign prostatic hyperplasia(BPH) histological features. Method: Forty-three patients who accepted prostatic biopsy were recruited in this study. All these patients were confirmed as BPH by pathological examination. MRI was introduced before biopsy, and the signal intensity of transitional zone/peripheral zone were recorded as a parameter to be compared within 3 pathological groups(adenomatous, interstitial, mixed). The area ratio of adenomatous components were calculated with IMAGE J software to detect the relevance of clinical data such as prostatic specific antigen(PSA), total prostate volume(TPV), International Prostatic Symptom Score(IPSS), residual urine volume(RUV). Result: There are significant differences in signal intensity of transitional zone/peripheral zone within 3 pathological groups. High signal intensity represented abundant adenomatous tissue. The area ratios of adenomatous components were related to PSA and TPV, but not to IPSS and RUV.Conclusion: MRI, a non-invasive and useful tool to predict the pathological component of BPH, would be of benefit to medication and treatment strategy.
- magnetic resonance imaging /
- benign prostatic hyperplasia /
- prostate tissue composition /
- prostate biopsy

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