-
摘要: 目的：通过观察早泄（PE）患者前列腺分泌指标的含量，探讨前列腺分泌功能与PE的相关性，为临床治疗PE提供一种新的思路。方法：选取2018年10月—2019年8月来我院就诊的80例PE患者作为观察组，以及同时期就诊的77例无PE的正常生育男性作为对照组。手淫法留取精液，离心分离精浆，分别测定两组精浆柠檬酸、ACP和锌的含量。统计学分析两组患者的精浆生化检查结果。结果：观察组精浆柠檬酸、酸性磷酸酶（ACP）及锌的含量分别为（22.28±15.65） mmol/L、（157.27±85.35） U/mL、（1.41±1.16） mmol/L，与对照组（29.08±13.72） mmol/L、（200.84±57.44） U/mL、（2.90±1.60） mmol/L相比均显著降低（P<0.01）。且观察组精浆柠檬酸、ACP及锌含量异常者分别为38例（47.5%）、38例（47.5%）、46例（57.5%），与对照组的9例（11.7%）、5例（6.5%）、14例（18.2%）比较，差异有统计学意义（P<0.01）。结论：PE患者精浆柠檬酸、ACP、锌的含量明显低于无PE者，提示前列腺分泌功能指标异常可能与PE的发病具有一定的相关性。Abstract: Objective: By observing the content of prostate secretion index in patients with premature ejaculation, to explore the correlation between prostate secretion function and premature ejaculation, and to provide a new way for clinical treatment of premature ejaculation.Methods: From October 2018 to August 2019, 80 patients with premature ejaculation as the observation group were selected in Shaanxi Traditional Chinese Medicine Hospital, and 77 normal fertile men without premature ejaculation were selected as the control group. The contents of citric acid, ACP and zinc in the seminal plasma of the two groups were measured respectively. The seminal plasma biochemical examination results of the two groups were statistically analyzed.Results: The contents of citric acid, ACP and zinc in the seminal plasma of the observation group were(22.28±15.65) mmol/L,(157.27 ±85.35) U/mL,(1.41±1.16) mmol/L, which were significantly lower than those of the control group(29.08±13.72) mmol/L,(200.84±57.44) U/mL,(2.90±1.60) mmol/L, respectively(P<0.01). There were 38 cases(47.5%), 38 cases(47.5%) and 46 cases(57.5%) with abnormal citric acid, ACP and zinc in seminal plasma of the observation group, while 9 cases(11.7%), 5 cases(6.5%) and 14 cases(18.2%) of the control group, respectively. The difference was statistically significant(P<0.01).Conclusion: The content of citric acid, ACP and zinc in seminal plasma of patients with premature ejaculation is significantly lower than that of patients without premature ejaculation, suggesting that the abnormality of prostate secretion may be related to the pathogenesis of premature ejaculation.
-
-
[1] Russo A, Capogrosso P, Ventimiglia E, et al.Efficacy and safety of dapoxetine in treatment of jaculation:an evidence-based review[J].Int J Clin Pract, 2016, 70(9):723-733.
[2] 中国中西医结合学会男科专业委员会.早泄中西医结合诊疗指南(试行版)[J].中华男科学杂志, 2018, 24(2):176-181.
[3] 邢俊平, 范晋海, 王明珠, 等.早泄病人慢性前列腺炎的发生率调查[J].中华男科学, 2003, 9(6):451-453.
[4] 黄小军, 李虎宜, 梁志恒, 等.早泄患者前列腺炎样症状及慢性前列腺炎患病状况临床调查[J].中国性科学, 2017, 26(8):8-10.
[5] Rowland DL, Cooper SE, Schneider M.Defining premature ejeculation for experimental and clinical investigation[J].Arch Sex Behav, 2001, 30(3):235-253.
[6] 陆金春.精液生化指标的全自动检测及临床应用[J].中华男科学杂志, 2018, 24(4):291-296.
[7] Althof SE, McMahon CG, Waldinger MD, et al.An Update of the International Society of Sexual Medicine's Guidelines for the Diagnosis and Treatment of Premature Ejaculation(PE)[J].Sex Med, 2014, 2(2):60-90.
[8] 赵国江, 郭强, 张雁钢.男性早泄诊疗进展综述[J].中国现代医生, 2018, 56(21):161-164.
[9] 付桥, 张景宇, 王芳芳, 等.达泊西汀联合坦索罗辛治疗早泄的应用效果及安全性研究[J].临床泌尿外科杂志, 2019, 34(10):786-790.
[10] 张培伦, 王鑫, 姚怀国, 等.前列腺指检按摩方法述评[J].健康研究, 2016, 36(5):517-519.
[11] 姚兵, 李西营, 赵志明, 等.早泄患者精浆生化指标测定及其意义[J].中华男科学杂志, 2007, 13(12):1084-1086.
[12] Aloosh M, Hassani M, Nikoobakht M.Seminal plasma magnesium and premature ejaculation:acase-control study[J].BJU Int, 2006, 98(2):402-404.
-
计量
- 文章访问数: 853
- PDF下载数: 441
- 施引文献: 0
下载: