Comparison of long-term survival between robotic and laparoscopic partial nephrectomy
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摘要: 目的:比较经机器人辅助肾部分切除术(RAPN)与经腹腔镜下肾部分切除术(LPN)的T1N0M0肾癌患者的远期生存。方法:收集2014年1月—2016年8月郑州大学第一附属医院216例经RAPN或LPN治疗的单侧T1N0M0(≤7 cm)肾肿瘤患者的临床、病理以及生存资料。依据手术方式不同分为RAPN组(n=90)与LPN组(n=126)。比较两组患者的临床病理特征以及生存差异,同时研究预后的影响因素。结果:216例肾癌患者的中位随访时间为4.9(2.5~6.4)年。RAPN组患者的年龄、BMI值和肿瘤平均直径均高于LPN组(P<0.05),两组总生存率、肿瘤特异生存率及无病生存率比较差异无统计学意义(P>0.05),多因素回归分析显示高龄和高Fuhrman分级是肿瘤特异性死亡的独立危险因素(P<0.05)。结论:RAPN患者的远期生存良好且与LPN的远期生存无明显差异。Abstract: Objective: To compare the long-term survival between robot-assisted partial nephrectomy(RAPN) and laparoscopic partial nephrectomy(LPN) on patients with T1N0M0renal cell carcinoma.Methods: The clinical and pathologic characteristics and survival data of 216 patients with unilateral T1N0M0(≤7 cm) renal cell carcinoma(RCC) treated with RAPN or LPN from Jan. 2014 to Aug. 2016 were completely collected. According to different surgical methods, they were divided into RAPN group(n=90) and LPN group(n=126). The clinicopathological characteristics and survival difference of the two groups were compared, and the factors affecting the prognosis were also studied.Results: Median follow-up time was 4.9(2.5-6.4) years of 216 patients. The age, BMI value and average tumor diameter of patients in RAPN group were higher than those in LPN group(P<0.05). There was no significant difference in overall survival, cancer-specific survival or disease-free survival between the two groups(P>0.05). Multivariate regression analysis showed that advanced age and high Fuhrman grade were independent risk factors for tumor-specific death(P<0.05).Conclusion: The long-term survival of RAPN is favorable and there is no significant difference from the long-term survival of LPN.
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