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摘要: 双极雄激素治疗(bipolar androgen therapy,BAT)是去势抵抗性前列腺癌(castration resistant prostate cancer,CRPC)的新疗法,可显著降低部分患者血清前列腺癌特异性抗原(prostate specific antigen,PSA)水平、提高患者生活质量和恢复去势治疗的敏感性,在CRPC患者的治疗中展现了巨大潜力,本文对BAT在前列腺癌中的相关研究进展作一综述。Abstract: Bipolar androgen therapy(BAT) is a novel treatment for castration resistant prostate cancer(CRPC), which can significantly reduce the level of prostate specific antigen in serum and improve the quality of life for patients. Now, there are significant advantages in the treatment of CRPC with BAT, so this article reviews the progress of clinical researchs of BAT in prostate cancer.
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