-
摘要: 耻骨上膀胱造瘘是一种常用的膀胱引流方法。与其他膀胱引流方法一样,耻骨上膀胱造瘘管引起的导管相关性感染很常见,且几乎无法避免。尽管目前已有许多研究进行了比较,耻骨上膀胱造瘘管与其他膀胱引流方法在控制导管相关性感染方面的优劣仍存在争议。此外,耻骨上膀胱造瘘相关性感染的病原菌谱和危险因素对于指导用药和护理、降低其相关性感染发生率至关重要,但目前在这方面的研究较少。本文将既往发表的相关研究作一综述,以期对留置耻骨上膀胱造瘘管引起的相关性感染有一个更深入的认识。Abstract: Suprapubic catheter is a commonly used method of bladder drainage. Like other bladder drainage methods, catheter-associated bacteriuria caused by suprapubic catheter is very common and almost unavoidable. Although there have been many studies that have compared it, the advantages and disadvantages of suprapubic catheter and other bladder drainage methods in decreasing catheter-associated bacteriuria are still controversial. In addition, the pathogen spectrum and risk factors of suprapubic catheter associated bacteriuria are essential for guiding medication and care, also for reducing the incidence of suprapubic catheter associated bacteriuria. This article will review the studies about suprapubic catheter associated bacteriuria.
-
表 1 对比SPC和IDC的CAB研究
第一作者 发表年份 前瞻性/回顾性 病例类型 导管留置时间 SPC IDC CAB CA-UTI CAB CA-UTI Kringel U [2] 2010 前瞻性 阴道前壁修补术 短期 96 h组:3.1%(1/32) 96 h组:0(0/32) 24 h组:27.0%(27/100);96 h组:25.0%(25/100) 24 h组:2.0%(2/100);96 h组:6.0%(6/100) Perrin LC [14] 1997 前瞻性 直肠手术 短期 14.3%(7/49) N/A 32.2%(19/59) N/A Sethia KK [13] 1987 前瞻性 普外科手术 短期 6.3%(2/32) N/A 47.1%(16/34) N/A Dinneen MD [15] 1990 回顾性 主动脉手术 短期 8.1%(7/86) N/A 35.6%(16/45) N/A Horgan AF [16] 1992 回顾性 急性尿储留 长期 17.9%(10/56) N/A 40.0%(12/30) N/A Harke N [17] 2018 前瞻性 前列腺癌根治术 短期 5.3%(3/57) N/A 10.1%(8/79) N/A Stekkinger E [18] 2011 前瞻性 阴道膨出修补术 短期 9.4%(6/64) N/A 9.7%(6/62) N/A Dunn TS [19] 2005 回顾性 Burch膀胱尿道固定术 短期 1.9%(2/106) N/A 2.7%(3/111) N/A Schiøtz HA[20] 1989 前瞻性 阴道整形术 短期 21.1%(8/38) 23.7%(9/38) 12.5%(5/40) 27.5%(11/40) Hennessey DB [21] 2018 回顾性 脊髓损伤 长期 N/A 29.2%(7/24) N/A 37.9%(11/29) Krebs J [22] 2016 回顾性 神经源性下尿路功能障碍 长期 N/A 58.3%(70/120) N/A 83.3%(15/18) 注:短期为≤14 d,长期为>14 d;N/A:未进行相关研究。 -
[1] Hunter KF, Bharmal A, Moore KN. Long-term bladder drainage: Suprapubic catheter versus other methods: a scoping review[J]. Neurourol Urodyn, 2013, 32(7): 944-551. doi: 10.1002/nau.22356
[2] Kringel U, Reimer T, Tomczak S, et al. Postoperative infections due to bladder catheters after anterior colporrhaphy: a prospective, randomized three-arm study[J]. Int Urogynecol J, 2010, 21(12): 1499-1504. doi: 10.1007/s00192-010-1221-2
[3] Leuck AM, Wright D, Ellingson L, et al. Complications of Foley catheters--is infection the greatest risk?[J]. J Urol, 2012, 187(5): 1662-1666. doi: 10.1016/j.juro.2011.12.113
[4] Bonkat G, Widmer AF, Rieken M, et al. Microbial biofilm formation and catheter-associated bacteriuria in patients with suprapubic catheterisation[J]. World J Urol, 2013, 31(3): 565-571. doi: 10.1007/s00345-012-0930-1
[5] Hooton TM, Bradley SF, Cardenas DD, et al. Diagnosis, prevention, and treatment of catheter-associated urinary tract infection in adults: 2009 International Clinical Practice Guidelines from the Infectious Diseases Society of America[J]. Clin Infect Dis, 2010, 50(5): 625-663. doi: 10.1086/650482
[6] Mermel LA, Allon M, Bouza E, et al. Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 Update by the Infectious Diseases Society of America[J]. Clin Infect Dis, 2009, 49(1): 1-45. doi: 10.1086/599376
[7] Bonfill X, Rigau D, Esteban-Fuertes M, et al. Efficacy and safety of urinary catheters with silver alloy coating in patients with spinal cord injury: a multicentric pragmatic randomized controlled trial. The ESCALE trial[J]. Spine J, 2017, 17(11): 1650-1657. doi: 10.1016/j.spinee.2017.05.025
[8] Hansson S, Jodal U, Lincoln K, et al. Untreated asymptomatic bacteriuria in girls: Ⅱ--Effect of phenoxymethylpenicillin and erythromycin given for intercurrent infections[J]. BMJ, 1989, 298(6677): 856-859. doi: 10.1136/bmj.298.6677.856
[9] Cai T, Mazzoli S, Mondaini N, et al. The role of asymptomatic bacteriuria in young women with recurrent urinary tract infections: to treat or not to treat?[J]. Clin Infect Dis, 2012, 55(6): 771-777. doi: 10.1093/cid/cis534
[10] Chong JT, Klausner AP, Petrossian A, et al. Pre-procedural antibiotics for endoscopic urological procedures: Initial experience in individuals with spinal cord injury and asymptomatic bacteriuria[J]. J Spinal Cord Med, 2015, 38(2): 187-192. doi: 10.1179/2045772313Y.0000000185
[11] Yuan W, Gu Y, Zhang K, et al. Postoperative Infection of Male Posterior Urethral Stenosis with Pelvic Fracture: A Retrospective Study from a Chinese Tertiary Teferral Center[J]. Urology, 2021, 154: 294-299. doi: 10.1016/j.urology.2021.04.021
[12] Gould CV, Umscheid CA, Agarwal RK, et al. Guideline for prevention of catheter-associated urinary tract infections 2009[J]. Infect Control Hosp Epidemiol, 2010, 31(4): 319-326. doi: 10.1086/651091
[13] Sethia KK, Selkon JB, Berry AR, et al. Prospective randomized controlled trial of urethral versus suprapubic catheterization[J]. Br J Surg, 1987, 74(7): 624-625.
[14] Perrin LC, Penfold C, McLeish A. A prospective randomized controlled trial comparing suprapubic with urethral catheterization in rectal surgery[J]. Aust N Z J Surg, 1997, 67(8): 554-556. doi: 10.1111/j.1445-2197.1997.tb02037.x
[15] Dinneen MD, Wetter LA, May AR. Urethral strictures and aortic surgery. Suprapubic rather than urethral catheters[J]. Eur J Vasc Surg, 1990, 4(5): 535-538. doi: 10.1016/S0950-821X(05)80798-4
[16] Horgan AF, Prasad B, Waldron DJ, et al. Acute urinary retention. Comparison of suprapubic and urethral catheterisation[J]. Br J Urol, 1992, 70(2): 149-151. doi: 10.1111/j.1464-410X.1992.tb15693.x
[17] Harke N, Godes M, Habibzada J, et al. Postoperative patient comfort in suprapubic drainage versus transurethral catheterization following robot-assisted radical prostatectomy: a prospective randomized clinical trial[J]. World J Urol, 2017, 35(3): 389-394. doi: 10.1007/s00345-016-1883-6
[18] Stekkinger E, van der Linden PJ. A comparison of suprapubic and transurethral catheterization on postoperative urinary retention after vaginal prolapse repair: a randomized controlled trial[J]. Gynecol Obstet Invest, 2011, 72(2): 109-116. doi: 10.1159/000323827
[19] Dunn TS, Figge J, Wolf D. A comparison of outcomes of transurethral versus suprapubic catheterization after Burch cystourethropexy[J]. Int Urogynecol J Pelvic Floor Dysfunct, 2005, 16(1): 60-62;discussion 62.
[20] Schiøtz HA, Malme PA, Tanbo TG. Urinary tract infections and asymptomatic bacteriuria after vaginal plastic surgery. A comparison of suprapubic and transurethral catheters[J]. Acta Obstet Gynecol Scand, 1989, 68(5): 453-455. doi: 10.3109/00016348909021020
[21] Hennessey DB, Kinnear N, MacLellan L, et al. The effect of appropriate bladder management on urinary tract infection rate in patients with a new spinal cord injury: a prospective observational study[J]. World J Urol, 2019, 37(10): 2183-2188. doi: 10.1007/s00345-018-02620-7
[22] Krebs J, Wöllner J, Pannek J. Risk factors for symptomatic urinary tract infections in individuals with chronic neurogenic lower urinary tract dysfunction[J]. Spinal Cord, 2016, 54(9): 682-686. doi: 10.1038/sc.2015.214
[23] Kidd EA, Stewart F, Kassis NC, et al. Urethral(indwelling or intermittent)or suprapubic routes for short-term catheterisation in hospitalised adults[J]. Cochrane Database Syst Rev, 2015, (12): CD004203.
[24] Dixon L, Dolan LM, Brown K, et al. RCT of urethral versus suprapubic catheterization[J]. Br J Nurs, 2010, 19(18): S7-S13.
[25] Jannelli ML, Wu JM, Plunkett LW, et al. A randomized controlled trial of clean intermittent self-catheterization versus suprapubic catheterization after urogynecologic surgery[J]. Am J Obstet Gynecol, 2007, 197(1): 72.e1-4. doi: 10.1016/j.ajog.2007.02.043
[26] Mitsui T, Minami K, Furuno T, et al. Is suprapubic cystostomy an optimal urinary management in high quadriplegics?A comparative study of suprapubic cystostomy and clean intermittent catheterization[J]. Eur Urol, 2000, 38(4): 434-438. doi: 10.1159/000020320
[27] Feneley RC, Hopley IB, Wells PN. Urinary catheters: history, current status, adverse events and research agenda[J]. J Med Eng Technol, 2015, 39(8): 459-470. doi: 10.3109/03091902.2015.1085600
[28] Sheriff MK, Foley S, McFarlane J, et al. Long-term suprapubic catheterisation: clinical outcome and satisfaction survey[J]. Spinal Cord, 1998, 36(3): 171-176. doi: 10.1038/sj.sc.3100536
[29] 王世平, 翟艳慧, 谢克亮. 耻骨上膀胱造瘘管细菌生物被膜的病原菌分布及耐药性研究[J]. 中华医院感染学杂志, 2013, 23(8): 1820-1822. https://www.cnki.com.cn/Article/CJFDTOTAL-ZHYY201308030.htm
[30] 林云侨, 陈锦添, 陈从其, 等. 膀胱造瘘管生物被膜相关感染特点及耐药性分析[J]. 中外医学研究, 2018, 16(13): 4-7. https://www.cnki.com.cn/Article/CJFDTOTAL-YJZY201813002.htm
[31] 李贵忠, 满立波, 黄广林. 长期耻骨上膀胱造瘘患者病原菌及药敏分析[J]. 临床泌尿外科杂志, 2015, 30(2): 153-155, 159. https://www.cnki.com.cn/Article/CJFDTOTAL-LCMW201502020.htm
[32] 张晓利, 唐盼盼, 刘玲只. 耻骨上膀胱造瘘长期置管并发感染状况调查分析[J]. 医药论坛杂志, 2012, 33(5): 117-118. https://www.cnki.com.cn/Article/CJFDTOTAL-HYYX201205069.htm
[33] Gunardi WD, Karuniawati A, Umbas R, et al. Biofilm-Producing Bacteria and Risk Factors(Gender and Duration of Catheterization)Characterized as Catheter-Associated Biofilm Formation[J]. Int J Microbiol, 2021, 2021: 8869275.
[34] Manohar J, Hatt S, DeMarzo BB, et al. Profiles of the bacterial community in short-term indwelling urinary catheters by duration of catheterization and subsequent urinary tract infection[J]. Am J Infect Control, 2020, 48(2): 178-183. doi: 10.1016/j.ajic.2019.08.005
[35] Belfield K, Kalith S, Aimar K, et al. Micro-organisms attached to the lumens and balloons of indwelling urinary catheters and correlation with symptoms, antibiotic use and catheter specimen of urine results[J]. J Med Microbiol, 2019, 68(4): 549-554. doi: 10.1099/jmm.0.000946
[36] Peng D, Li X, Liu P, et al. Epidemiology of pathogens and antimicrobial resistanceof catheter-associated urinary tract infections in intensivecare units: A systematic review and meta-analysis[J]. Am J Infect Control, 2018, 46(12): e81-e90. doi: 10.1016/j.ajic.2018.07.012
[37] Maharjan G, Khadka P, Siddhi Shilpakar G, et al. Catheter-Associated Urinary Tract Infection and Obstinate Biofilm Producers[J]. Can J Infect Dis Med Microbiol, 2018, 2018: 7624857.
[38] Subramanian P, Shanmugam N, Sivaraman U, et al. Antiobiotic resistance pattern of biofilm-forming uropathogens isolated from catheterised patients in Pondicherry, India[J]. Australas Med J, 2012, 5(7): 344-348. doi: 10.4066/AMJ.2012.1193
[39] Holá V, Ruzicka F, Horka M. Microbial diversity in biofilm infections of the urinary tract with the use of sonication techniques[J]. FEMS Immunol Med Microbiol, 2010, 59(3): 525-528.
[40] Baan AH, Vermeulen H, van der Meulen J, et al. The effect of suprapubic catheterization versus transurethral catheterization after abdominal surgery on urinary tract infection: a randomized controlled trial[J]. Dig Surg, 2003, 20(4): 290-295.
[41] Bochicchio GV, Joshi M, Shih D, et al. Reclassification of urinary tract infections in critically ill trauma patients: a time-dependent analysis[J]. Surg Infect(Larchmt), 2003, 4(4): 379-385.
[42] Cardosi RJ, Cardosi RP, Grendys EC Jr, et al. Infectious urinary tract morbidity with prolonged bladder catheterization after radical hysterectomy[J]. Am J Obstet Gynecol, 2003, 189(2): 380-383;discussion 383-384.
[43] Esclarín De Ruz A, García Leoni E, Herruzo Cabrera R. Epidemiology and risk factors for urinary tract infection in patients with spinal cord injury[J]. J Urol, 2000, 164(4): 1285-1289.
[44] Rogers RG, Kammerer-Doak D, Olsen A, et al. A randomized, double-blind, placebo-controlled comparison of the effect of nitrofurantoin monohydrate macrocrystals on the development of urinary tract infections after surgery for pelvic organ prolapse and/or stress urinary incontinence with suprapubic catheterization[J]. Am J Obstet Gynecol, 2004, 191(1): 182-187.
[45] van der Kooi TI, de Boer AS, Manniёn J, et al. Incidence and risk factors of device-associated infections and associated mortality at the intensive care in the Dutch surveillance system[J]. Intensive Care Med, 2007, 33(2): 271-278.
[46] Wilde MH, Carrigan MJ. A chart audit of factors related to urine flow and urinary tract infection[J]. J Adv Nurs, 2003, 43(3): 254-262.