肾孤立性纤维性肿瘤的影像学及病理学特征(附1例报告并文献复习)

余杨; 刘继红; 万婕; 王少刚; 余虓

肾孤立性纤维性肿瘤的影像学及病理学特征(附1例报告并文献复习)

- 1. 华中科技大学同济医学院附属同济医院超声影像科(武汉, 430030);
- 2. 华中科技大学同济医学院附属同济医院泌尿外科;
- 3. 华中科技大学同济医学院附属同济医院病理科

详细信息

通讯作者: 刘继红,E-mail:jhliu@tjh.tjmu.edu.cn

中图分类号: R737.11

收稿日期: 2013-09-20

Histopathologic and imageological features of solitary fibrous tumor of the kidney (One case report and literature review)

- 1. Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China;
- 2. Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology;
- 3. Department of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

More Information

Corresponding author: LIU Jihong, E-mail: jhliu@tjh.tjmu.edu.cn

Received Date: 20 September 2013

摘要

摘要: 目的：探讨肾孤立性纤维性肿瘤的影像学特征、病理学特征。方法：对1例直径1 cm肾孤立性纤维性肿瘤患者术前进行彩色超声、CT及MRI检查，术后进行病理学观察及免疫组化标记，并结合相关文献进行分析。结果：影像学检查提示为肾实质性肿瘤。术后病理检查显示梭形肿瘤细胞排列无明显特征，但含有较丰富的薄壁血管和灶性胶原纤维束；瘤细胞表现温和，界限不清晰，胞质红染，核仁不明显，核分裂象少见，免疫组织化学检查：CD34、vimentin、bcl-2、CD99、CD10均阳性，CD31、SMA、desmin、S-100、PCK、EMA、CD21、CD23均阴性，Ki-67增殖指数为5%。结论：原发性肾孤立性纤维性肿瘤临床十分罕见，小肿瘤的影像学表现可能有某些特征，但仍需要病理学检查确诊。
- 肾肿瘤 /
- 孤立性纤维性肿瘤 /
- 影像学 /
- 病理学
Abstract: Objective: To explore the histopathologic and imageological features of solitary fibrous tumor (SFT) of the kidney. Method: One case of SFT of the kidney with 1 cm in diameter was detected by ultrasound, abdominal CT and MRI preoperatively. Postoperative pathological examination was also taken. Then relevant literatures were reviewed as a referrence to the data of the patient.Result: Imageological examinations showed renal parenchymatous tumor. On pathologic examination, spindle tumor cells were arranged in no particular pattern, with numerous thin-walled vessels and collagen fiber bundle. It also showed that tumor cells were mild with obscure boundary, eosinophilic cytoplasm, inconspicuous nucleoli and rare mitosis. Immunohistochemical staining showed that CD34+, vimentin+, bcl-2+, CD99+, CD10+, CD31-, SMA-, desmin-, S-100-, PCK-, EMA-, CD21-, CD23-. Proliferation index of Ki-67 was 5%.Conclusion: Primary solitary fibrous tumor of the kidney is very rare. Some characteristics of such small tumors may be seen through imageological examinations, but the final diagnosis still depends on pathological examinations.
- kidney neoplasms /
- solitary fibrous tumor /
- imageology /
- pathology

HTML全文

参考文献(11)

[1]	Bruzzone A, Varaldo M, Ferrarazzo C, et al. Solitary fibrous tumor[J]. Rare Tumors, 2010, 2(4):e64.
[2]	Sasaki H, Kurihara T, Katsuoka Y, et al. Distant metastasis from benign solitary fibrous tumor of the kidney[J]. Case Rep Nephrol Urol, 2013, 3(1):1-8.
[3]	林玲,范钦,黄波涛.肾脏原发性孤立性纤维性肿瘤3例报道并文献复习[J]. 临床与实验病理学杂志, 2012, 28(6):672-674.
[4]	王鸿雁,邓元.肾脏巨大恶性孤立性纤维瘤的临床病理分析[J]. 肿瘤防治研究, 2011, 38(2):174-178.
[5]	徐衍盛,路汉军,刘萃龙等.肾恶性孤立性纤维瘤1例[J]. 武警医学, 2012, 23(7):615-616.
[6]	Khater N, Khauli R, Shahait M, et al. Solitary fibrous tumors of the kidneys:presentation, evaluation, and treatment[J]. Urol Int, 2013, 29.[Epub ahead of print]
[7]	Johnson T R, Pedrosa I, Goldsmith J, et al. Magnetic resonance imaging findings in solitary fibrous tumor of the kidney[J]. Journal of Computer Assisted Tomography, 2005, 29(4):481-483.
[8]	李苏建,陈英鑫,袁彩云. 肾脏孤立性纤维瘤影像诊断[J]. 放射性实践, 2007, 22(6):591-593.
[9]	韩远远,李勇,吴卓. 肾孤立性纤维瘤的影像学诊断:附1例报告并文献复习[J]. 岭南现代临床外科, 2012, 10(6):471-472.
[10]	丁永玲,周晓明,王艳芬等.肾脏原发性孤立性纤维性肿瘤临床病理学分析[J]. 临床与实验病理学杂志, 2008, 24(6):749-751.
[11]	黄海建,曲利娟,郑智勇. 孤立性纤维性肿瘤研究进展[J]. 现代肿瘤医学, 2011, 19(6):1255-1258.