前列腺液中性粒细胞弹性蛋白酶在Ⅲ型前列腺炎诊断中的意义

董治春; 崔喆; 杨长海; 李黎明

前列腺液中性粒细胞弹性蛋白酶在Ⅲ型前列腺炎诊断中的意义

- 天津医科大学总医院泌尿外科(天津, 300052)

详细信息

通讯作者: 杨长海,E-mail:ych609@eyou.com

中图分类号: R697

收稿日期: 2012-09-08

The significance of neutrophil elastase in the diagnosis of type Ⅲ prostatitis

- 1. Department of Urology, Tianjin Medical University General Hospital, Tianjin, 300052, China

More Information

Corresponding author: YANG Changhai, E-mail: ych609@eyou.com

Received Date: 08 September 2012

摘要

摘要: 目的：探讨中性粒细胞弹性蛋白酶（neutrophil elastase， NE）在Ⅲ型前列腺炎诊断中的意义。方法：ⅢA型36例与ⅢB型87例分别进行前列腺按摩液（expressed prostatic secretion，EPS）细菌培养、EPS常规检查、NIH-前列腺炎症状评分（NIH-CPSINE）、NE浓度的测定，然后行独立样本t检验和简单相关分析。正常对照组84例同样进行上述检查后分别与ⅢA型和ⅢB型进行独立样本t检验。结果：①ⅢA型和ⅢB型患者EPS中NE（t=6.32，P<0.05）差异有统计学意义，NE与白细胞呈现明显的正相关关系（r=0.878，P<0.05），两者CPSI（t=1.85，P>0.05）比较差异无统计学意义。②ⅢA型和对照组患者EPS中白细胞（t=13.74，P<0.05）、NE（t=6.499，P<0.05）、CPSI（t=23.76，P<0.05）差异有统计学意义。ⅢB型和对照组患者EPS中NE（t=2.14，P<0.05）、CPSI（t=33.15，P<0.05）差异有统计学意义，白细胞（t=1.49，P>0.05）无统计学意义。结论：NE在Ⅲ型前列腺炎的诊断中能够作为一个很有意义的指标，而NE浓度与白细胞呈较强的正比关系，提示NE浓度的高低能够反映出慢性前列腺炎的严重程度。
- Ⅲ型前列腺炎 /
- 弹性蛋白酶 /
- 白细胞 /
- 相关性 /
- 诊断
Abstract: Objective: To explore the significance of Neutrophil Elastase (NE) in the diagnosis of type Ⅲ prostatitis.Method: The level of NE, EPS routine, bacterial culture and CPSI were first detected in 36 cases of type Ⅲ A and 87 cases of type Ⅲ B, then the results of two groups were analyzed by independent samples t-test and the relation between level of NE and the number of leukocyte was evaluated. Normal control group of 84 cases were done by same method of two experimental groups, and the results were analyzed by independent samples t-test with the experimental group respectively.Result: ①There were significant differences in level of NE (t=6.32, P<0.05) between ⅢA and Ⅲ B groups. There was a obviously positive relation between the level of NE and the number of leukocyte in test group (r=0.878, P<0.05). The CPSI (t=1.85, P>0.05) between ⅢA and Ⅲ B groups was not statistically significant. ②The level of leukocyte (t=13.74, P<0.05), NE (t=6.499, P<0.05), CPSI (t=23.76, P<0.05) were statistically significant between ⅢA and the control group. The NE concentration (t=2.14, P<0.05) and CPSI (t=33.15, P<0.05) were statistically significant between ⅢB and control group, while the number of leukocyte (t=1.49, P>0.05) was not statistically significant.Conclusion: The data presented here indicated that the level of NE in EPS has some significance in the diagnosis of type ⅢA and ⅢB prostatitis. There was a strong positive relation between NE concentration and the number of leukocyte, which showed the level of NE concentration could reflect the severity of chronic prostatitis.
- type Ⅲ prostatitis /
- neutrophil elastase /
- leukocyte /
- correlation /
- diagnosis

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