Cao Z, Robinson R A. The role of proteomics in understanding biological mechanisms of sepsis[J]. Proteomics Clin Appl, 2014, 8(1-2):35-52. 2 孙颖浩, 那彦群, 叶章群, 等主编. 2014版中国泌尿外科疾病诊断治疗指南[M]. 北京:人民卫生出版社,2014:428. 3 Reinhart K, Bauer M, Riedemann N C, et al. New approaches to sepsis:molecular diagnostics and biomarkers[J]. Clin Microbiol Rev, 2012, 25(4):609-634. 4 Goller C C, Arshad M, Noah J W, et al. Lifting the mask:identification of new small molecule inhibitors of uropathogenic Escherichia coli group 2 capsule biogenesis[J]. PLoS One, 2014, 9(7):e96054. 5 Su L, Cao L, Zhou R, et al. Identification of novel biomarkers for sepsis prognosis via urinary proteomic analysis using iTRAQ labeling and 2D-LC-MS/MS[J]. PLoS One, 2013, 8(1):e54237. 6 Marx G, Reinhart K. Urosepsis:from the intensive care viewpoint.Int[J]. J Antimicrob Agents, 2008, 31 Suppl 1:S79-84. 7 Degoricija V, Sharma M, Legac A, et al. Survival analysis of 314 episodes of sepsis in medical intensive care unit in university hospital:impact of intensive care unit performance and antimicrobial therapy[J]. Croat Med J, 2006, 47(3):385-397. 8 Book M, Lehmann L E, Schewe J C, et al. Urosepsis. Current therapy and diagnosis[J]. Urologe A, 2005, 44(4):413-422. 9 Wagenlehner F M, Weidner W, Naber K G, et al. Pharmacokinetic characteristics of antimicrobials and optimal treatment of urosepsis[J]. Clin Pharmacokinet, 2007, 46(4):291-305. 10 Burekovic A, Dizdarevic-Bostandzic A, Godinjak A, et al. Poorly regulated blood glucose in diabetic patients——predictor of acute infections[J]. Med Arh, 2014, 68(3):163-166. 11 Al-Badr A, Al-Shaikh G. Recurrent Urinary Tract Infections Management in Women:A review[J]. Sultan Qaboos Univ Med J, 2013, 13(3):359-367. 12 Foxman B, Barlow R, Arcy H, et al. Urinary tract infection:self-reported incidence and associated costs[J]. Ann Epidemiol, 2000, 10:509-515. 13 Filiatrault L, McKay R M, Patrick D M, et al. Antibiotic resistance in isolates recovered from women with community-acquired urinary tract infectionspresenting to a tertiary care emergency department[J]. CJEM, 2012, 14(5):295-305. 14 Kalra O P, Raizada A. Approach to a patient with urosepsis[J]. J Glob Infect Dis, 2009, 1(1):57-63. 15 Zhou J, Qian C, Zhao M, et al. Epidemiology and outcome of severe sepsis and septic shock in intensive care units in mainland China[J]. PLoS One, 2014, 9(9):e107181. 16 Wagenlehner F M, Lichtenstern C, Rolfes C, et al. Diagnosis and management for urosepsis[J]. Int J Urol, 2013, 20(10):963-970. 17 Youssef R F, Neisius A, Goldsmith Z G. et al. Clinical outcomes after ureteroscopic lithotripsy in patients who initially presented with urosepsis:matched pair comparison with elective ureteroscopy[J]. J Endourol, 2014, 28(12):1439-1443. 18 Carmignani L, Picozzi S, Spinelli M, et al. Bacterial sepsis following prostatic biopsy[J]. Int Urol Nephrol, 2012, 44(4):1055-1063. 19 Wagenlehner F M, Pilatz A, Waliszewski P, et al. Infection and sepsis prevention in prostate biopsy[J]. Urologe A, 2013, 52(10):1459-1468; quiz 1467-1468. 20 Abbott K C, Oliver J D, Hypolite I, et al. Hospitalizations for bacterial septicemia after renal transplantation in the united states[J]. Am J Nephrol, 2001, 21:120-127. 21 Yacoub R, Akl N K. Urinary Tract Infections and Asymptomatic Bacteriuria in Renal Transplant Recipients[J]. J Glob Infect Dis, 2011, 3(4):383-389. 22 Muller V, Becker G, Delfs M, et al. Heemann U. Do urinary tract infections trigger chronic kidney transplant rejection in man[J]? J Urol, 1998, 159:1826-1829. 23 Gołebiewska J E, Debska-Slizień A, Rutkowski B.. Urinary tract infections during the first year after renal transplantation-one centre's experience and a review of the literature[J]. Clin Transplant, 2014, 28(11):1263-1270. 24 Nabbout P, Slobodov G, Mellis A M. et al. Percutaneous nephrolithotomy in spinal cord neuropathy patients:a single institution experience[J]. J Endourol, 2012, 26(12):1610-1613. 25 Lipsky B A. Urinary tract infections in men. Epidemiology, pathophysiology, diagnosis, and treatment[J]. Ann Intern Med, 1989, 110:138-150. 26 Al-Badr A, Al-Shaikh G. Recurrent Urinary Tract Infections Management in Women:A review[J]. Sultan Qaboos Univ Med J, 2013, 13(3):359-367. 27 Langley R J, Tsalik E L, Velkinburgh J C, et al. An integrated clinico-metabolomic model improves prediction of death in sepsis[J]. Sci Transl Med, 2013, 5(195):195ra95. 28 Ragnarsdóttir B, Lutay N, Grönberg-Hernandez J. Genetics of innate immunity and UTI susceptibility[J]. Nat Rev Urol, 2011, 8(8):449-468. 29 Ramakrishna K, Pugazhendhi S, Kabeerdoss J, et al. Association between heat shock protein 70 gene polymorphisms and clinical outcomes in intensive care unit patients with sepsis[J]. Indian J Crit Care Med, 2014, 18(4):205-211. 30 Ani C, Farshidpanah S, Bellinghausen Stewart A, et al. Variations in organism-specific severe sepsis mortality in the United States:1999-2008[J]. Crit Care Med, 2015, 43(1):65-77. 31 胡云建,俞云松,张秀珍,等. 产超广谱β-内酰胺酶细菌的分子流行病学研究[J]. 中华医院感染学杂志, 2004, 14(3):241-244. 32 Park I H, Lee S H, Yu S T, et al. Serum procalcitonin as a diagnostic marker of neonatal sepsis[J]. Korean J Pediatr, 2014, 57(10):451-456. 33 Nargis W, Ibrahim M, Ahamed B U. Procalcitonin versus C-reactive protein:Usefulness as biomarker of sepsis in ICU patient[J]. Int J Crit Illn Inj Sci, 2014, 4(3):195-199. 34 Bouchon A, Facchetti F, Weigand M A, et al. TREM-1 amplifies inflammation and is a crucial mediator of septic shock[J]. Nature, 2001, 410(6832):1103-1107. 35 Reinhart K, Bauer M, Riedemann N C, et al. New approaches to sepsis:molecular diagnostics and biomarkers[J]. Clin Microbiol Rev, 2012, 25(4):609-634. 36 王宝海,侯海峰,刘川,等. 血清降钙素原在诊断尿脓毒血症中的意义[J]. 重庆医科大学学报, 2014, 39(6):812-815. 37 龚宾宾,郝宗耀,施浩强,等. 血清内毒素检测在经皮肾镜碎石术后感染诊断中的临床意义[J]. 临床泌尿外科杂志,2014, 29(9):800-801. 38 Sugimoto K, Adomi S, Koike H, et al. Procalcitonin as an indicator of urosepsis[J]. Res Rep Urol, 2013, 5:77-80. 39 Nargis W, Ibrahim M, Ahamed B U, et al. Procalcitonin versus C-reactive protein:Usefulness as biomarker of sepsis in ICU patient[J]. Int J Crit Illn Inj Sci, 2014, 4(3):195-199. 40 Malkova O G, Leiderman I N, Levit A L, et al. Changes in lipid and carbohydrate metabolism in patients with severe sepsis of different etiology[J]. Anesteziol Reanimatol, 2014, (2):15-21. 41 陈南晖,张仕萍,彭红. C-反应蛋白对感染性和非感染性发热鉴别价值[J]. 重庆医科大学学报,2010(11):1722-1724. 42 Li H X, liu Z M, Zhao S J, et al. Measuring borth procalcitonin and C-reactive protein for a diagnosis of sepsis in critically ill patient[J]. J Int Med Res, 2014, 42(4):1050-1059. 43 Sherwin C, Broadbent R, Young S, et al. Utility of interleukin-12 and interleukin-10 in comparison with other cytokines and acute-phase reactants in thediagnosis of neonatal sepsis[J]. Am J Perinatol, 2008, 25(10):629-636. 44 胡大军,柳永兵. 连续性血液净化治疗尿脓毒血症导致多器官功能障碍综合征12例临床分析[J]. 重庆医科大学学报, 2012, 37(4):373-375. 45 Andaluz-Ojeda D, Bobillo F, Iglesias V, et al. A combined score of pro-and anti-inflammatory interleukins improves mortality prediction in severe sepsis[J]. Cytokine, 2012, 57:332-336. 46 Qureshi S S, Lewis S M, Gant V A, et al. Increased distribution and expression of CD64 on blood polymorphonuclear cells from patients with the systemic inflammatory response syndrome (SIRS)[J]. Clin Exp Immunol, 2001, 125(2):258-265. 47 Gros A, Roussel M, Sauvadet E, et al. The sensitivity of neutrophil CD64 expression as a biomarker of bacterial infection is low in critically ill patients[J]. Intensive Care Med, 2012, 38(3):445-452. 48 Gaini S, Koldkjaer O G, Pedersen C, et al. Procalcitonin, lipopolysaccharide-binding protein, interleukin-6 and C-reactive protein in community-acquired infections and sepsis:a prospective study[J]. Crit Care, 2006, 10(2):R53. 49 Gros A, Roussel M, Sauvadet E. The sensitivity of neutrophil CD64 expression as a biomarker of bacterial infection is low in critically ill patients[J]. Intensive Care Med, 2012, 38(3):445-452. 50 Gámez-Díaz L Y, Enriquez L E, Matute J D. Diagnostic accuracy of HMGB-1, sTREM-1, and CD64 as markers of sepsis in patients recently admitted to the emergency department[J]. Acad Emerg Med, 2011, 18(8):807-815. 51 Sakr Y, Burgett U, Nacul F E, et al. Lipopolysaccharide binding protein in a surgical intensive care unit:a marker of sepsis[J]? Crit Care Med, 2008, 36:2014-2022. 52 How C K, Hou S K, Shih H C, et al. Expression profile of MicroRNAs in gram-negative bacterial sepsis[J]. Shock, 2015, 43(2):121-127. 53 Wagenlehner F M, Lichtenstern C, Weigand M A, et al. Urosepsis and treatment[J]. Urologe A, 2010, 49(5):618-622. 54 Wagenlehner F M, Lichtenstern C, Rolfes C, et al. Diagnosis and management for urosepsis[J]. Int J Urol, 2013, 20(10):963-970. 55 刘凌琪,杨嗣星,吴天鹏. 孤立肾结石患者电子输尿管软镜钬激光碎石术后出现尿脓毒血症的诊治分析[J]. 临床泌尿外科杂志, 2013, 28(12):897-902. 56 李为兵. 经皮肾镜碎石取石术并发症及其预防[J]. 中华泌尿外科杂志, 2012, 33(1):32-33. 57 Su L, Cao L, Zhou R, et al. Identification of novel biomarkers for sepsis prognosis via urinary proteomic analysis using iTRAQ labeling and 2D-LC-MS/MS[J]. PLoS One, 2013, 8(1):e54237. 58 Paiva R A, David C M, Domont G B. Proteomics in sepsis:a pilot study[J]. Rev Bras Ter Intensiva, 2010, 22(4):403-412. 59 Cao Z, Robinson R A. The role of proteomics in understanding biological mechanisms of sepsis[J]. Proteomics Clin Appl, 2014, 8(1-2):35-52. 60 Cao Z, Yende S, Kellum J A, et al. Proteomics reveals age-related differences in the host immune response to sepsis[J]. J Proteome Res, 2014, 13(2):422-432. 61 Su L, Zhou R, Liu C, et al. Urinary proteomics analysis for sepsis biomarkers with iTRAQ labeling and two-dimensional liquid chromatography-tandem mass spectrometry[J]. J Trauma Acute Care Surg, 2013, 74(3):940-945.