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摘要: 目的:探讨三维能量多普勒超声预测经尿道前列腺电切术 (TURP) 术中出血的价值。方法:本实验对115例BPH患者术前进行超声检查, 获得血管形成指数 (VI) 、血流指数 (FI) 、血管形成血流指数 (VFI) 、阻力指数 (RI) 及收缩期峰值血流速度 (PSV) 。TURP术中记录出血相关参数;术后切除标本计数MVD。比较超声定量参数、术中出血参数及微血管密度 (MVD) 的相关性。结果:VI、VFI与切除单位重量前列腺组织出血量正相关, 相关系数为0.882、0.885 (P<0.01);与MVD正相关, 相关系数为0.870、0.830 (P<0.01) 。VI、VFI作为预测TURP术中出血量超过300ml的指标时, 敏感性为0.692和0.641, 特异性为0.697及0.737。结论:三维能量多普勒超声对评估前列腺内的血流具有临床意义。Abstract: Objective:To investigate the effect of three-dimensional power doppler ultrasonography (3D-PDU) on predicting the intraoperative bleeding in TURP.Method:One hundred and fifteen patients were enrolled.The vascularization index (VI), flow index (FI), vascularization flow index (VFI) were measured using 3D-PDU.Resistant index (RI) and peak systolic velocity (PSV) were also measured.All blood parameters associated with intraoperative bleeding were obtained during surgery.Microvessel density (MVD) was calculated using cluster of differentiation 34 (CD34) immunoreactivity.The relationships among ultrasound parameters, parameters related to intraoperative bleeding and MVD were assessed.Result:VI and VFI were positively correlated with blood loss of resecting 1g prostate tissue (BL/g) (P<0.01), also positively correlated with MVD (P<0.01).The sensitivity of VI and VFI as the indicators of intraoperative bleeding>300ml were 0.692 and 0.641 respectively, and the specificity were 0.697 and 0.737 respectively.Conclusion:Using 3D-PDU to assess vascularization in prostate shows clinical significance.
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