保留肾单位手术治疗完全内生性中央型肾肿瘤20例报告

何跃; 张海梁; 秦晓健; 施国海; 朱煜; 叶定伟

doi:10.13201/j.issn.1001-1420.2018.04.019

保留肾单位手术治疗完全内生性中央型肾肿瘤20例报告

- 1. 遂宁市中心医院泌尿外科(四川遂宁, 629000);
- 2. 复旦大学附属肿瘤医院泌尿外科

详细信息

通讯作者: 叶定伟,E-mail:dwyeli@163.com

中图分类号: R737.11

收稿日期: 2017-01-22

Nephron sparing surgery in the treatment of complete endophytic and central renal tumor:report of 20 cases

- 1. Department of Urology, Suining Central Hospital, Suining, Sichuan, 629000, China;
- 2. Department of Urology, Fudan University Shanghai Cancer Center

More Information

Corresponding author: YE Dingwei, E-mail: dwyeli@163.com

Received Date: 22 January 2017

摘要

摘要: 目的:探讨完全内生性中央型肾肿瘤行保留肾单位手术的安全性和有效性。方法:回顾性分析2014年1月~2016年12月保留肾单位手术治疗的20例完全内生性中央型肾肿瘤患者的临床资料。患者男13例,女7例;年龄35~71岁,平均(51.6±10.3)岁;肿瘤位于左侧12例,右侧8例;BMI 20.8~27.1kg/m²,平均(24.1±2.0) kg/m²;肿瘤最大直径1.0~4.0cm,平均(2.5±0.8) cm。结果:本组患者手术时间8~130min,平均(106±12.0) min;肾动脉阻断时间18~31min,平均(21.5±3.3) min。术后均未出现漏尿、血尿及出血。病理手术切缘均为阴性。术后6个月血清肌酐和肾小球滤过率(eGFR)与术前比较差异均无统计学意义(P＞0.05)。随访6~33个月,中位随访时间20个月,20例未发现局部复发和远处转移。结论:保留肾单位的肿瘤切除术是治疗内生性中央型肾肿瘤的有效手段,但仍需大样本多中心研究及长时间随访观察远期疗效。
- 内生性 /
- 中央型 /
- 肾肿瘤 /
- 保留肾单位手术
Abstract: Objective: To investigate the safety and efficacy of nephron sparing surgery in the treatment of complete endophytic and central renal tumors.Method: We retrospectively analysed 20 cases of complete endophytic and central renal tumor treated by nephron sparing surgery from January 2014 to December 2016 including 13 males and 7 females.Their age range was 35-71 (mean, 51.6) years old.Tumors of 12 cases were located on the left and 8 right.BMI was 20.8-27.1 (mean, 24.1) kg/m².The maximum diameter of tumor was 1.0-4.0 (mean, 2.5) cm.Result: Operation time was 80-130 (average, 106) min.Renal artery occlusion time was 18-31 (average, 21.5) min.There was no leakage of urine, hematuria or hemorrhage after operation.The postoperative pathology showed that surgical margins were all negative.All cases were followed up for 6-33 (median, 20) months.There was no significant difference in serum creatinine and glomerular filtration rate between before and 6 months after the operation (P＞0.05). All 20 patients weren't found local recurrence or distant metastasis.Conclusion: Nephron sparing surgery is an effective method for the treatment of complete endophytic and central renal tumors.The long-term efficacy needs a large number of samples and multicenter study.
- endophytic /
- central /
- renal tumor /
- nephron spring surgery

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