肥大细胞与免疫性前列腺炎的关系研究进展

张勇; 张力; 梁朝朝

doi:10.13201/j.issn.1001-1420.2018.08.018

肥大细胞与免疫性前列腺炎的关系研究进展

- 安徽医科大学第一附属医院泌尿外科(合肥, 230022)
基金项目:
国家自然科学基金项目(编号81630019)

详细信息

通讯作者: 梁朝朝,E-mail:Liang_chaozhao@163.com

中图分类号: R697.33

收稿日期: 2018-04-11

Mast cells and immune prostatitis

- Department of Urology, First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China

More Information

Corresponding author: LIANG Chaozhao, E-mail: Liang_chaozhao@163.com

Received Date: 11 April 2018

摘要

摘要: 慢性前列腺炎(CP)是泌尿外科常见和多发病,在成年男性中发病率约12%,目前其病因机制尚不清楚。近年来,有学者开始研究免疫因素与其发病关系,并证实了在CP的发生发展中都会伴随着免疫细胞及细胞因子的精细调控,同时炎性因子与免疫细胞相互作用也促进了CP的发展。肥大细胞(MC)是构成机体免疫系统重要组成部分,与多种免疫疾病有关。随着对CP发病机制免疫学方面的不断深入,了解MC在CP中的作用对研究CP相关靶向治疗及其分型尤为重要。本文就MC在CP发病机制中的作用及其与CP的相关症状以及治疗等方面的关系进行综述。
- 慢性前列腺炎 /
- 肥大细胞 /
- 细胞因子 /
- 自身免疫
Abstract: Chronic prostatitis (CP) is a common and frequently-occurring disease in urology.The incidence rate in adult males is about 12%.The etiology and mechanism of the disease are still unclear.In recent years, some scholars have begun to study the relationship between immune factors and its onset, and confirmed that the occurrence and development of CP are accompanied by fine regulation of immune cells and cytokines, and the interaction between inflammatory factors and immune cells also promotes the development of CP.Mast cells (MC) constitute an important part of the body's immune system and are involved in a variety of immune diseases.With the deepening of the immunological aspects of the pathogenesis of CP, the role of MC in CP is more recognized, which is particularly important for the study of CP-related targeted therapy and its classification.This article reviews the role of MC in the pathogenesis of CP and its relationship with CP related symptoms and treatment.
- chronic prostatitis /
- mast cells /
- cytokines /
- autoimmunity

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