Learning curve of laparoscopic radical cystectomy for a single surgeon of 118 consecutive cases
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摘要: 目的:回顾性分析我院单一术者连续行腹腔镜膀胱癌根治术(LRC)患者的临床资料,评估学习曲线的影响。方法:我院2014年2月~2018年3月接受LRC患者118例,男98例,女20例;其中90例行回肠膀胱术,21例行输尿管皮肤造口术,7例行原位回肠新膀胱术。按时间顺序将病例分为3组(第1组第1~40例,第2组第41~80例,第3组第81~118例),比较3组的手术时间、术中出血等方面的差异。结果:3组患者平均手术时间为(295.59±56.59) min;平均术中出血为(353.64±163.19) ml。第1组、第2组和第3组的平均手术时间分别为(338.00±50.00) min、(283.50±50.55) min和(263.68±40.63) min,第1组与第2组比较差异有统计学意义(P<0.05),第2组与第3组比较差异无统计学意义(P>0.05)。第1组、第2组和第3组的平均出血量分别为(448.00±224.38) ml、(327.25±107.63) ml和(282.11±57.43) ml,术中出血量逐渐下降,而手术时间在40例后呈稳定趋势。结论:LRC治疗膀胱肿瘤是安全有效的,学习曲线相对陡峭。当达到40例手术的积累后,熟练程度明显提高。Abstract: Objective: To evaluate our experience and results of laparoscopic radical cystectomy (LRC) and assess the impact of learning curve on perioperative outcomes with LRC by a single-surgeon's experience in Peking Union Medical College Hospital.Method: Between February 2014 and March 2018, aprospective study in a single institute on patients with bladder cancer who underwent LRC was conducted.One hundred and eighteen patients (98 men and 20 women) underwent LRC during the 4-year study period.Ninety patients were submitted to ileal conduits, 21 patients to ureterocutaneostomies, and 7 to neobladders.The patients were divided into 3 groups according to the time of operation.Operative parameters and perioperative complications were evaluated including operative time, blood loss and perioperative complications.Result: The mean operative time was (295.59±56.59) min, and the mean blood loss was (353.64±163.19) ml.The operative time was (338.00±50.00), (283.50±50.55) and (263.68±40.63) minutes, respectively, for each group.The intraoperative blood loss was (448.00±224.38), (327.25±107.63) and (282.11±57.43) ml, respectively, for each group.The intraoperative blood loss was gradually lowered from group one to group three.Significant decline of operative time occurred after every40 cases of LRC (P<0.05).Conclusion: LRC is a safe and efficient modality of treatment of bladder cancer.However, it comes with a steep learning curve.This report helps to define the learning curve for LRC and demonstrates an acceptable level of proficiency by the 40 th case.
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Key words:
- bladder cancer /
- laparoscopy /
- cystectomy /
- learning curve
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