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摘要: 尿失禁(UI)是前列腺癌根治术(RP)后的常见并发症之一,严重影响患者术后的生活质量。RP术后尿控的恢复与患者术前的基本情况、手术方案以及有效的术后管理相关。RP术后UI的治疗方法包括生活方式干预、盆底肌功能锻炼、药物等保守治疗以及人工尿道括约肌(AUS)植入术、填充剂注射术、尿道压迫及吊带术等外科治疗。干细胞治疗压力性尿失禁(SUI)因其微创、高效日益受到人们重视,有研究表明干细胞治疗RP术后SUI同样有效。本文主要对RP后UI预防和治疗方面的研究进展作一综述。Abstract: Urinary incontinence(UI) is one of the common complications after radical prostatectomy(RP), which seriously affect the life quality of postoperative patients. The recovery of UI after RP is related to the preoperative basic situation, surgical protocols and effective postoperative management. The therapy of UI after RP includes conservative treatments(lifestyle intervention, pelvic floor muscle exercise and drugs) and surgical treatments(artificial urethral sphincter implantation, bulking agents injection and urethral sling). Stem cell therapy for stress urinary incontinence(SUI) has attracted more and more attention due to its minimal invasion and high efficiency, and studies have shown that stem cell therapy is equally effective for SUI after RP. This review focuses on the progress in the prevention and treatment of UI after RP.
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