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摘要: 膀胱癌是世界上最常见的癌症之一。研究表明膀胱癌是一组具有不同临床病程和不同治疗反应的分子异质性疾病,其发生发展与多条分子通路相关。利用分子生物学技术对膀胱癌进行分子分型有望提高疾病的诊治水平。本文综述了近年来膀胱癌分子病理学和膀胱癌分子亚型分类的研究进展。Abstract: Bladder cancer is one of the most common cancers in the world. Studies have shown that bladder cancer is a group of molecular heterogeneous diseases with different clinical courses and treatment responses, and its occurrence and development are related to multiple molecular pathways. Molecular classification of bladder cancer by molecular biology is expected to improve the diagnosis and treatment of the disease. This paper reviews the recent advances in molecular pathology and subtype classification of bladder cancer.
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Key words:
- bladder cancer /
- molecular subtype /
- molecular pathway /
- mutation spectrum
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