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摘要: 长链非编码RNA(long non-coding RNA,lncRNA)是一类转录本长度>200 nt的不编码蛋白质的RNA分子。近年来研究发现长链非编码RNA在诸多肿瘤的发生发展过程中发挥重要作用。lncRNA SNHG3是一种近年被广泛探究的典型lncRNA。研究不断深入,lncRNASNHG3被发现可能与人体各系统中肿瘤的发生发展有关,如消化系统、呼吸系统、神经系统、生殖系统、泌尿系统等,且机制各异,可能为多种肿瘤的治疗提供新的潜在治疗靶点,有着广泛的研究前景。本文结合国内外最新报道,就lncRNA SNHG3影响多种肿瘤发生发展的最新研究进展进行简要综述。Abstract: Long non-coding RNA(lncRNA) is a class of RNA molecules that do not encode proteins with transcripts longer than 200 nt. Recent studies have found that lncRNAs play an important role in the occurrence and development of many tumors. lncRNA SNHG3 is a typical lncRNA that has been widely explored in recent years. With the deepening of research, lncRNA SNHG3 has been found to be related to the occurrence and development of tumors in various human systems, such as the digestive system, respiratory system, nervous system, reproductive system and urinary system. Treatment offers new potential therapeutic targets and has extensive research prospects. Based on the latest reports at home and abroad, this article briefly reviews the latest research progress on the influence of SNHG3 on the development of multiple tumors.
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Key words:
- SNHG3 /
- lncRNA /
- tumor /
- research progress
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