Clinical efficacy of gas-bladder laparoscopic Politano-Leadbetter for congenital malformation of vesicoureteral junction in children
-
摘要: 目的 比较气膀胱下Politano-Leadbetter与Cohen输尿管再植术治疗小儿膀胱输尿管连接部异常的临床疗效。方法 回顾性分析我院2016年1月—2020年3月收治的51例膀胱输尿管连接部异常的患儿,早期24例行Cohen术式,后期27例采用Politano-Leadbetter术,术后随访6个月~3年,比较2组手术时长、术中出血量、术后住院时间、并发症及术后输尿管扩张恢复情况。结果 51例患儿均在气膀胱下顺利完成手术,无一例中转开腹,2组手术时间[(114.42±29.84) min vs (129.59±47.42) min,P=0.18]、术中出血量[(5.88±4.81) mL vs (5.81±4.25) mL,P=0.96]、术后住院时间[(10.17±2.65) d vs (10.56±3.23) d,P=0.64]比较差异无统计学意义;所有患儿拔除尿管后排尿通畅,无尿漏。2组患儿各有2例术后出现尿路感染1次,2组并发症发生率差异无统计学意义(P=0.32)。术后1、3、6个月定期复查泌尿系超声,2组患儿术后输尿管扩张情况均较术前好转,48例完全恢复,3例部分恢复;其中Cohen组2例,Politano-Leadbetter组1例,术前均为巨输尿管,术后6个月复查排尿性膀胱泌尿道造影(VCUG)均未见反流,2组输尿管恢复情况差异无统计学意义(P=0.59)。结论 气膀胱下Politano-Leadbetter术治疗小儿膀胱输尿管连接部异常的临床疗效确切、安全有效,具有微创优势的特点;同时Politano-Leadbetter术的输尿管符合自然生理解剖特点,在输尿管游离范围、裁剪及黏膜下隧道长度方面具有Cohen术所不具备的优势,值得临床推广。Abstract: Objective To compare the clinical efficacy between laparoscopic Politano-Leadbetter and Cohen ureteric reimplantation for congenital malformation of vesicoureteral junction in children.Methods A retrospective analysis of 51 patients who underwent ureteric reimplantation from January 2016 to March 2020 was conducted. The first 24 cases were given Cohen procedure, while the remaining 27 cases underwent Politano-Leadbetter procedure. The follow-up period was 6 months to 3 years. Comparisons in terms of operative duration, blood loss, hospital stay, complication rate and postoperative ureteral dilatation were made.Results All 51 cases underwent ureteric reimplantation successfully, and none of them were transferred to open surgery. No significant differences were found in operation time ([114.42±29.84] min vs [129.59±47.42]min, P=0.18), blood loss ([5.88±4.81] mL vs [5.81±4.25] mL, P=0.96), hospital stay ([10.17±2.65] d vs [10.56±3.23] d, P=0.64) between the groups. All children had no obstructed urination or urinary leakage after removing the catheter. There was no significant difference in the incidence of complications between the two groups (P=0.32). After 1 month, 3 months, 6 months, ureteral dilatation of 48 cases recovered completely and 3 cases partially recovered. Among the two groups, there was no significant difference in ureteral recovery (P=0.59).Conclusion The procedure of Politano-Leadbetter is an effective and safe option for congenital malformation of vesicoureteral junction in children. The operation has the characteristics of minimally invasive advantages. Compared with Cohen, Politano-Leadbetter is easier to operate in terms of natural physiological anatomy, so it is worthy of clinical promotion.
-
-
表 1 2组一般资料比较
例,X±S 组别 性别 年龄/月 病种 双侧病变 输尿管平均最大直径/mm 男 女 原发性膀胱输尿管反流 膀胱输尿管连接部狭窄 是 否 A组(24例) 17 7 15.54±9.07 19 5 7 17 11.44±6.25 B组(27例) 16 11 20.29±12.66 20 7 8 19 11.18±6.36 P值 0.38 0.45 0.67 0.97 0.89 表 2 2组手术结果比较
例(%),X±S 组别 手术时间/min 手术出血量/mL 术后住院时间/d 手术并发症 输尿管恢复情况 完全恢复 部分恢复 A组(24例) 114.42±29.84 5.88±4.81 10.17±2.65 2(8.3) 22(91.7) 2(8.3) B组(27例) 129.59±47.42 5.81±4.25 10.56±3.23 2(7.4) 26(96.3) 1(3.7) P值 0.18 0.96 0.64 0.32 0.59 -
[1] Gimpel C, Masioniene L, Djakovic N, et al. Complications and long-term outcome of primary obstructive megaureter in childhood[J]. Pediatr Nephrol, 2010, 25(9): 1679-1686. doi: 10.1007/s00467-010-1523-0
[2] Yeung CK, Sihoe JD, Borzi PA. Endoscopic cross-trigonal ureteral reimplantation under carbon dioxide bladder insufflation: a novel technique[J]. J Endourol, 2005, 19(3): 295-299. doi: 10.1089/end.2005.19.295
[3] Marchini GS, Hong YK, Minnillo BJ, et al. Robotic assisted laparoscopic ureteral reimplantation in children: case matched comparative study with open surgical approach[J]. J Urol, 2011, 185(5): 1870-1875. doi: 10.1016/j.juro.2010.12.069
[4] 吴谋东, 占雄, 毕允力, 等. 气膀胱腹腔镜Cohen术治疗小儿膀胱输尿管连接处畸形的疗效[J]. 中华实用儿科临床杂志, 2017, 32(19): 1503-1505. doi: 10.3760/cma.j.issn.2095-428X.2017.19.015
[5] 徐延波, 陈海琛, 马丽丽, 等. 气膀胱下Politano-Leadbetter输尿管移植术的经验分析[J]. 临床小儿外科杂志, 2020, 19(8): 741-745, 758. doi: 10.3969/j.issn.1671-6353.2020.08.015
[6] Kanojia RP, Pandey A, Bawa M. Robotic Assisted Vesicoscopic Cohen's Reimplantation in Pediatric Patient: Nuances of Technique, Experience, and Outcome[J]. J Laparoendosc Adv Surg Tech A, 2020, 30(10): 1137-1141. doi: 10.1089/lap.2020.0401
[7] Yaǧız B, Demirel BD. Ureteral reimplantation aligned laparoscopically: Pneumovesicoscopic Politano-Leadbetter reimplantation in children[J]. J Pediatr Urol, 2021, 17(3): 413. e1-413. e8. doi: 10.1016/j.jpurol.2021.02.007
[8] Liu X, Liu JH, Zhang DY, et al. Retrospective study to determine the short-term outcomes of a modified pneumovesical Glenn-Anderson procedure for treating primary obstructing megaureter[J]. J Pediatr Urol, 2015, 11(5): 266. e1-6. doi: 10.1016/j.jpurol.2015.03.020
[9] Zhu X, Wang J, Zhu H, et al. Lich-Gregoir vesico-ureteral reimplantation for duplex kidney anomalies in the pediatric population: a retrospective cohort study between laparoscopic and open surgery[J]. Transl Pediatr, 2021, 10(1): 26-32. doi: 10.21037/tp-20-163
[10] 毕允力, 阮双岁, 肖现民, 等. 气膀胱腹腔镜输尿管移植术[J]. 中华小儿外科杂志, 2006, 27(2): 78-80. doi: 10.3760/cma.j.issn.0253-3006.2006.02.007
[11] 张旭辉, 王计文, 李龙, 等. 气膀胱腹腔镜Cohen输尿管移植术治疗先天性膀胱输尿管连接部梗阻[J]. 临床小儿外科杂志, 2010, 9(3): 182-183.
[12] Krambeck AE, Gettman MT, BaniHani AH, et al. Management of nephrolithiasis after Cohen cross-trigonal and Glenn-Anderson advancement ureteroneocystostomy[J]. J Urol, 2007, 177(1): 174-178. doi: 10.1016/j.juro.2006.08.112
[13] 孙颖浩, 许传亮, 高旭, 等. 膀胱黏膜肌瓣翻转术在抗膀胱输尿管返流术中的应用(附四例报告)[J]. 中华泌尿外科杂志, 2003, 24(4): 263-265. doi: 10.3760/j:issn:1000-6702.2003.04.018
[14] Chung MS, Han SW, Jung HJ, et al. Transvesicoscopic ureteral reimplantation in children with bilateral vesicoureteral reflux: surgical technique and results[J]. J Laparoendosc Adv Surg Tech A, 2012, 22(3): 295-300. doi: 10.1089/lap.2011.0318
[15] 曾莉, 黄一东, 康磊, 等. 改良Politano-Leadbetter术治疗儿童原发性输尿管膀胱连接处异常[J]. 中国修复重建外科杂志, 2015, 29(10): 1279-1283. doi: 10.7507/1002-1892.20150277
[16] Grimsby GM, Dwyer ME, Jacobs MA, et al. Multi-institutional review of outcomes of robot-assisted laparoscopic extravesical ureteral reimplantation[J]. J Urol, 2015, 193(5 Suppl): 1791-1795.
[17] Choi H, Park JY, Bae JH. Initial experiences of lapaoscopic intravesical detrusorraphy using the Politano-Leadbetter technique[J]. J Pediatr Urol, 2016, 12(2): 110. e1-110. e7. doi: 10.1016/j.jpurol.2015.07.014
[18] Baek M, Han DH. Transvesicoscopic Politano-Leadbetter ureteral reimplantation in children with vesicoureteral reflux: A novel surgical technique[J]. Investig Clin Urol, 2019, 60(5): 405-411. doi: 10.4111/icu.2019.60.5.405
[19] 毕允力. 腹腔镜膀胱输尿管反流手术操作技术规范[J]. 中华小儿外科杂志, 2020, 41(2): 100-106.
[20] Tekgül S, Riedmiller H, Hoebeke P, et al. EAU guidelines on vesicoureteral reflux in children[J]. Eur Urol, 2012, 62(3): 534-542. doi: 10.1016/j.eururo.2012.05.059
-