前列腺电切术后MRS的随访研究

刘洋; 梁华庚; 张士龙; 杨军; 洪弘长; 徐红卫; 邢永生; 牛俊喜; 曾甫清

前列腺电切术后MRS的随访研究

- 1. 郑州大学第五附属医院磁共振中心(郑州, 450052);
- 2. 华中科技大学同济医学院附属协和医院泌尿外科;
- 3. 河南省人民医院泌尿外科
基金项目:
湖北省自然科学基金（编号2010CDB07704）

详细信息

通讯作者: 曾甫清,E-mail:zengfuqing@163.com

中图分类号: R737.25

收稿日期: 2012-12-21

The follow-up study of magnetic resonance spectroscopy in patients undergoing transurethral resection of prostate

- 1. Department of MR Center, the Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China;
- 2. Department of University, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology;
- 3. Department of Urology, Henan Provincial People's Hospital

More Information

Corresponding author: ZENG Fuqing, E-mail: zengfuqing@163.com

Received Date: 21 December 2012

摘要

摘要: 目的：采用MRS随访前列腺电切术后特征代谢物变化。方法：收集10例前列腺电切术后患者，其中5例前列腺增生，5例前列腺癌，应用MRS分析代谢物不同。结果：前列腺增生可有明显枸橼酸盐峰增高，前列腺癌有明显胆碱峰增高，两者特征代谢物有明显差异。结论：MRS能特异、便捷的了解前列腺电切术后的前列腺疾病复发，进展情况。
- 前列腺癌 /
- 前列腺增生 /
- 磁共振波谱
Abstract: Objective: Apply MRS to study the change of Characterized metabolites in patients undergoing TURP.Method: Collect 9 patients, 5 with benign prostatic hyperplasia and 4 with prostate cancer, and apply magnetic resonance spectroscopy to analysis the different characterized metabolites.Result: The choline peak rise in patients with benign prostatic hyperplasia, while citrate peak obviously rise in patients with prostate cancer.Conclusion: Magnetic resonance spectroscopy may find out the prostate disease recurrence and progress after transurethral resection easily and specifically.
- prostate cancer /
- benign prostatic hyperplasia /
- magnetic resonance spectroscopy

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参考文献(11)

[1]	那彦群,叶章群,孙光.2011版中国泌尿外科疾病诊断治疗指南[M]. 北京:人民卫生出版社, 2011:49-50.
[2]	Catalona W J, Smith D S, Ratliff T L, et al. Detection of organ-confined prostate cancer is increased through prostate specific antigen-based screening[J]. JAMA,1993, 270:948-954.[ZK)]
[3]	Mohan P M, Hosur R V. Structure-function-folding relationships and native energy landscape of dynein light chain protein:nuclear magnetic resonance insights[J]. J Biosci, 2009, 34:465-479.
[4]	Weidner A, Michaely H J, Pelzer A, et al. Imaging of prostate cancer by diagnostic radiology and nuclear medicine[J]. Aktuelle Urol, 2010, 41:35-42.
[5]	Caivano R, Cirillo P, Balestra A, et al. Prostate cancer in magnetic resonance imaging:diagnostic utilities of spectroscopic sequences[J]. J Med Imaging Radiat Oncol, 2012,56:606-616.
[6]	Bulik M, Jancalek R, Vanicek J,et al.Potential of MR spectroscopy for assessment of glioma grading[J].Clin Neurol Neurosurg. 2013,115:146-153.
[7]	Ljungberg M, Westberg G, Vikhoff-Baaz B,et al. 31P MR spectroscopy to evaluate the efficacy of hepatic artery embolization in the treatment of neuroendocrine liver metastases[J].Acta Radiol,2012,53:1118-1126.
[8]	Shin H J, Baek H M, Ahn J H, et al.Prediction of pathologic response to neoadjuvant chemotherapy in patients with breast cancer using diffusion-weighted imaging and MRS[J].NMR Biomed, 2012,25:1349-1359.
[9]	Le Q T, Koong A, Lieskovsky Y Y, et al. In vivo 1H magnetic resonance spectroscopy of lactate in patients with stage IV head and neck squamous cell carcinoma[J]. Int J Radiat Oncol Biol Phys,2008,71:1151-1157.
[10]	Tiwari P, Kurhanewicz J, Madabhushi A. Multi-kernel graph embedding for detection, Gleason grading of prostate cancer via MRI/MRS[J]. Med Image Anal, 2013, 17:219-235.
[11]	Kurth J,Defeo E,Cheng L L.Magnetic resonance spectroscopy:a promising tool for the diagnostics of human prostate cancer[J].Urol Oncol,2011,29:562-571.