Clinical significance of peritoneal integrity reserving in radical cystectomy and ileal conduit
-
摘要: 目的:探讨肌层浸润性膀胱癌行根治性膀胱切除加回肠膀胱术保留腹膜完整性,对患者术后庝痛、胃肠功能恢复和肠梗阻等并发症的发生率的影响。方法:行根治性膀胱切除回肠膀胱术中,根据腹膜破损及修复情况设计为腹膜完整组和腹膜非完整组,其中腹膜完整组30例,腹膜非完整组37例;比较两组平均手术时间、出血量、术后庝痛时间、镇痛剂应用时间、保留胃管时间、排便时间、肠道功能恢复时间、住院时间及肠梗阻等并发症发生率等参数。结果:两组平均手术时间、出血量差异无统计学意义(P>0.05),术后庝痛时间、镇痛药物使用时间、保留胃管时间、排便时间、胃肠功能恢复、住院时间及肠梗阻(3.3%,22.0%)等并发症发生率差异有统计学意义(P<0.05)。结论:根治性膀胱切除回肠膀胱术保留腹膜完整性不影响手术时间和出血量,可以减轻术后庝痛、有利于术后肠道恢复及降低肠梗阻发生率,缩短住院时间。Abstract: Objective: To investigate the impact of peritoneal integrity retaining in the surgery of radical cystectomy and ileal conduit,on the postoperative pain,recovery of gastrointestinal function and the incidence of intestinal obstruction and other complications. Method: According to the breakage of the peritoneal in the opration, 67 cases were divided into two goups:the peritoneal complete group(30 cases) and peritoneal non-intact group(37 cases). The significant markers and therapeutic results were recorded and analyzed, which includes mean operative time, intraoperative blood loss, postoperative pain, analgesics requirement, use of gastric tube, defecation, recovery of intestinal function, length of stay and the incidence of intestinal obstruction and other complication rate. Result: There was no significant difference in the mean operation time, intraoperative blood loss between two groups (P> 0.05). The peritoneal complete group showed statistically significant better results on postoperative pain, analgesics requirement, the use of gastric tube, defecation, recovery of intestinal function, length of stay and the incidence of intestinal obstruction(3.3%, 22.0%) and other complications (P<0.05). Conclusion: Radical cystectomy and ileal conduit with keeping the integrity of the peritoneal does not affect the mean operation time, intraoperative blood loss. It has the advantages of less postoperative pain, shorter recovery of intestinal function, less incidence of intestinal obstruction and shorter length of stay.
-
Key words:
- bladder tumor /
- radical cystectomy /
- ileal conduit /
- peritoneal /
- complication
-
-
[1] Shimko M S, Tollefson M K, Umbreit E C, et al. Long-term complications of conduit urinary diversion[J]. J Urol, 2011, 185:562-567.
[2] Stenzl A, Cowan N C, De Santis M, et al. Treatment of muscle-invasive and metastatic bladder cancer:update of the EAU guidelines[J]. Eur Urol, 2011, 59:1009-1018.
[3] Nieuwenhuijzen J A, de Vries R R, Bex A, et al. Urinary diversions after cystectomy:the association of clinical factors, complications and functional results of four different diversions[J]. Eur Urol, 2008, 53:834-842; discussion 842-844.
[4] Nabi G, Yong S M, Ong E, et al. Is orthotopic bladder replacement the new gold standard? Evidence from a systematic review[J]. J Urol, 2005, 174:21-28.
[5] Aragona F, De Caro R, Parenti A, et al. Structural and ultrastructural changes in ileal neobladder mucosa:a 7-year follow-up[J]. Br J Urol, 1998, 81:55-61.
[6] Serel T A, Sevin G, Perk H, et al. Antegrade extraperitoneal approach to radical cystectomy and ileal neobladder[J]. Int J Urol, 2003, 10:25-28.
[7] 李成龙, 冷金花, 李孟慧, 等. 转化生长因子β/Smad信号传导系统在子宫内膜异位症盆腔粘连患者腹膜中的表达及其意义[J]. 中华妇产科杂志, 2011, 46(11):826-830.
[8] Chegini N. TGF-beta system:the principal profibrotic mediator of peritoneal adhesion formation[J]. Semin Reprod Med, 2008, 26:298-312.
[9] Chegini N. Peritoneal molecular environment, adhesion formation and clinical implication[J]. Front Biosci, 2002, 7:e91-115.
[10] van Goor H. Consequences and complications of peritoneal adhesions[J]. Colorectal Dis, 2007, 9 Suppl 2:25-34.
[11] Ellis H, Moran B J, Thompson J N, et al. Adhesion-related hospital readmissions after abdominal and pelvic surgery:a retrospective cohort study[J]. Lancet, 1999, 353:1476-1480.
[12] Demco L. Pain mapping of adhesions[J]. J Am Assoc Gynecol Laparosc, 2004, 11:181-183.
[13] Menzies D. Postoperative adhesions:their treatment and relevance in clinical practice[J]. Ann R Coll Surg Engl, 1993, 75:147-153.
[14] Holmdahl L E, Al-Jabreen M, Risberg B. Role of fibrinolysis in the formation of postoperative adhesions[J]. Wound Repair Regen, 1994, 2:171-176.
[15] Holmdahl L, Eriksson E, al-Jabreen M, et al. Fibrinolysis in human peritoneum during operation[J]. Surgery, 1996, 119:701-705.
[16] Sajja S B, Schein M. Early postoperative small bowel obstruction[J]. Br J Surg, 2004, 91:683-691.
-
计量
- 文章访问数: 94
- PDF下载数: 115
- 施引文献: 0