肾嗜酸细胞腺瘤的诊疗分析(附8例报告)

王萱; 朱生才; 刘明; 万奔; 魏东; 朱刚; 王建业

肾嗜酸细胞腺瘤的诊疗分析(附8例报告)

- 1. 北京协和医学院研究生院(北京, 100730);
- 2. 北京医院泌尿外科

详细信息

通讯作者: 朱生才,E-mail:zhu0821@yahoo.com.cn

中图分类号: R737.11

收稿日期: 2012-01-14

Diagnosis and treatment of renal oncocytoma (Report of 8 cases)

- 1. Postgraduate Institution of Peking Union Medical College, Beijing, 100730, China;
- 2. Department of Urology, Beijing Hospital

More Information

Corresponding author: ZHU Shengcai, E-mail: zhu0821@yahoo.com.cn

Received Date: 14 January 2012

摘要

摘要: 目的：探讨肾嗜酸细胞腺瘤的临床、影像学及病理特点，提高肾嗜酸细胞腺瘤的诊治水平。方法：回顾性分析8例肾嗜酸细胞腺瘤患者的临床资料。临床表现为左腰痛1例，腰酸及镜下血尿1例，余6例由体检发现。8例均行超声和CT检查，1例行MRI及IVP检查。5例术前诊断为肾癌，2例术前怀疑肾癌，但良性病变不除外，1例诊断为肾盂癌。5例行肾部分切除术，2例行根治性肾切除术，1例行腹腔镜肾、输尿管及部分膀胱切除术。结果：术后病理检查均诊断为肾嗜酸细胞腺瘤。肉眼观察肿瘤边界清楚；光镜下见肿瘤无明显异型性和核分裂相；电镜下胞浆内见大量线粒体。术后随访2个月~7年，所有病例均未出现复发和转移。结论：肾嗜酸细胞腺瘤是一种较少见的肾脏良性肿瘤，多无明显临床症状；影像学检查有阳性发现，但在区分良恶性上不可靠；确诊有赖于病理检查。治疗上首选保留肾单位手术，术中冷冻病理切片可对手术提供重要信息，其预后良好，但应密切随访。
- 肾肿瘤 /
- 嗜酸细胞腺瘤 /
- 诊断
Abstract: Objective: To discuss the clinical,imageology and pathological features of renal oncocytoma and to analyze ways to improve the diagnosis and treatment of renal oncocytoma.Method: Eight cases of renal oncocytoma clinical data were retrospectively analyzed,of which 1 case showed left lumbar pain,1 presented with lumbar soreness and microscopic hematuria,and the rest 6 cases were diagnosed by physical examination.Ultrasound and CT scan were performed in all 8 cases and 1 of the cases also with MRI and IVP.5 cases were diagnosed renal cell carcinoma preoperatively,2 patients were suspected renal cell carcinoma but benign lesions could not be excluded and 1 case was diagnosed renal pelvis carcinoma.Nephron sparing surgery was performed in 5 cases;2 cases underwent radical nephrectomy and the other one which was diagnosed renal pelvis carcinoma underwent laparoscopic nephroureterectomy.Result: All cases were confirmed as renal oncocytoma by postoperative pathology.All tumors had clear borders that can be defined by naked eyes.Microscopically,the tumors didn't have significant atypia and mitotic.Enormous mitochondria were noted on electron microscopy.The follow-up of the cases lasted for 2 months to 7 years and no recurrence or metastasis were found.Conclusion: Renal oncocytoma is a rare type of benign tumor,and has no obvious clinical symptoms.Imaging features have positive findings,but do not reliably distinguish between the benign and the malignant;the exact diagnosis is based on pathological examination.Nephron sparing surgery is the primary and effective therapeutic method.Intraoperative frozen section and pathology may provide important information for the operation.The prognosis of renal oncocytoma is good and regular follow-up is needed.
- renal tumor /
- oncocytoma /
- diagnose

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