经直肠超声造影与经直肠常规超声诊断前列腺癌的比较研究

张帆; 汪维; 黄海锋; 常小峰; 郭宏骞

doi:10.13201/j.issn.1001-1420.2014.09.002

经直肠超声造影与经直肠常规超声诊断前列腺癌的比较研究

- 南京大学医学院附属鼓楼医院泌尿外科(南京, 210008)

详细信息

通讯作者: 郭宏骞,E-mail:dr.ghq@163.com

中图分类号: R737.25

收稿日期: 2014-02-17

修回日期: 2014-07-11

Comparative study between transrectal contrast-enhanced ultrasound and routine transrectal ultrasound in the diagnosis of prostate cancer

- Department of Urology, Nanjing Drum Tower Hospital, Affiliated Hospital of Nanjing University Medical School, Nanjing, 210008, China

More Information

Corresponding author: GUO Hongqian, E-mail: dr.ghq@163.com

Received Date: 17 February 2014

Revised Date: 11 July 2014

摘要

摘要: 目的：比较经直肠超声造影与经直肠常规超声诊断前列腺癌的各自优势。方法：选择前列腺癌患者213例，年龄54~83岁，平均71岁。检测PSA为4.12~150.00 μg/L，平均22.53 μg/L。先行经直肠常规超声检查，再行经直肠前列腺超声造影检查，绘制时间强度曲线（TIC曲线），分别判读常规超声和超声造影结果。随后行12针前列腺系统穿刺活检。结果：213例患者中，常规超声诊断前列腺癌123例，超声造影诊断前列腺癌113例，穿刺活检病理确诊前列腺癌99例。常规超声与病理检查的诊断符合率为53.52%，超声造影与病理检查的诊断符合率为80.28%。两种诊断方法敏感度、特异度、假阳性率、假阴性率、漏诊率、病理检查符合率差异均有统计学意义（P<0.05）。结论：经直肠超声造影可灵敏显示前列腺血流分布情况，对前列腺癌的诊断有较高的准确性，值得推广使用。
- 前列腺癌 /
- 常规超声 /
- 超声造影 /
- 前列腺穿刺活检
Abstract: Objective: To evaluate the advantages of transrectal contrast-enhanced ultrasound compared with routine transrectal ultrasound in the diagnosis of prostate cancer.Method: We selected 213 cases with prostate cancer whose mean age was 71 (range, 54-83) years. Their PSAs were from 4.12 to 150 (average, 22.53) μg/L. All patients were examined by routine transrectal ultrasound and transrectal contrast-enhanced ultrasound, and the time-intensity curve (TIC) was drawn. Then, the diagnoses of routine ultrasound and contrast-enhanced ultrasound were made. Subsequently, 12-core systemic prostate biopsy was taken.Result: All 213 patients, 123 cases were diagnosed with prostate cancers by routine ultrasound, 113 cases were diagnosed with prostate cancers by contrast-enhanced ultrasound, and 99 cases were diagnosed with prostate cancers by pathology. The coincidence rate of routine ultrasound and pathology was 53.52%, and the coincidence rate of contrast-enhanced ultrasound and pathology was 80.28%. P values of the sensitivities, specificities, false positive rates, false negative rates, rates of misdiagnosis, pathological coincidence rates between transrectal contrast-enhanced ultrasound and routine transrectal ultrasound were less than 0.05, which meant there were significant differences.Conclusion: Transrectal contrast-enhanced ultrasound can show the distribution of blood flow in prostate sensitively. It is worth promoting for it can diagnose prostate cancer accurately.
- prostate cancer /
- routine ultrasound /
- contrast-enhanced ultrasound /
- prostate biopsy

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