Preliminary analysis of the efficacy of micro-radio frequency in the treatment of female refractory overactive bladder
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摘要: 为了分析膀胱微射频治疗女性难治性膀胱过度活动症(OAB)的疗效并确定未来的研究重点，选取了2021年3月—2022年1月浙江省人民医院门诊行该疗法治疗的30例女性OAB患者，共行4次治疗以及14周随访，并比较患者首次治疗前后的排尿日记数据和完成整个阶段治疗前后膀胱过度活动症评分(OABSS)和膀胱状态患者感知度调查表(PPBC)。结果显示, 经首次治疗后患者排尿日记数据比较差异有统计学意义(P< 0.05)；完成了整个阶段治疗后患者OABSS评分和PPBC评分比较差异亦有统计学意义(P< 0.05)。提示膀胱微射频疗法对女性难治性OAB的症状改善有一定程度上的疗效，但长期的治疗效果仍需进一步观察和研究，相对于其他治疗方式也需进一步对比。Abstract: In order to analyze the efficacy of micro-radio frequency in the treatment of female refractory overactive bladder (OAB) and determine the focus of future research, 30 female OAB patients were treated for 4 times with this therapy in the outpatient clinic of Zhejiang Provincial People's Hospital from March 2021 to January 2022 and followed up for 14 weeks. The voiding diary data before and after the first treatment and the OABSS score and PPBC score before and after the whole stage of treatment were compared. The results showed that there was significant difference in voiding diary data after the first treatment (P< 0.05), OABSS score and PPBC score after the whole stage of treatment (P< 0.05). It is suggested that micro-radio frequency therapy can improve the symptoms of female refractory OAB to a certain extent, but the long-term therapeutic effect still needs further observation, study, and further comparison with other treatment methods.
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[1] Tu LM, De Wachter S, Robert M, et al. Initial clinical experience with selective bladder denervation for refractory overactive bladder[J]. Neurourol Urodyn, 2019, 38(2): 644-652. doi: 10.1002/nau.23881
[2] Rovner ES, Versi E, Le Mai T, et al. One-year results with selective bladder denervation in women with refractory overactive bladder[J]. Neurourol Urodyn, 2019, 38(8): 2178-2184. doi: 10.1002/nau.24110
[3] 佟凯军. OAB症状评分表对BPH治疗指导作用相关研究[D]. 天津医科大学, 2012.
[4] Hsiao SM, Liao CH, Lin HH, et al. Duration of Antimuscarinic Administration for Treatment of Overactive Bladder Before Which One Can Assess Efficacy: An Analysis of Predictive Factors[J]. Int Neurourol J, 2015, 19(3): 171-177. doi: 10.5213/inj.2015.19.3.171
[5] Gormley EA, Lightner DJ, Burgio KL, et al. Diagnosis and treatment of overactive bladder(non-neurogenic)in adults: AUA/SUFU guideline[J]. J Urol, 2012, 188(6 Suppl): 2455-2463.
[6] Brubaker L, Fanning K, Goldberg EL, et al. Predictors of discontinuing overactive bladder medications[J]. BJU Int, 2010, 105(9): 1283-1290. doi: 10.1111/j.1464-410X.2009.09035.x
[7] Shim SR, Cho YJ, Shin IS, et al. Efficacy and safety of botulinum toxin injection for interstitial cystitis/bladder pain syndrome: a systematic review and meta-analysis[J]. Int Urol Nephrol, 2016, 48(8): 1215-1227. doi: 10.1007/s11255-016-1295-y
[8] 王磊, 宋奇翔, 程欣, 等. 骶神经调节术治疗女性膀胱过度活动症及间质性膀胱炎/膀胱疼痛综合征的疗效分析[J]. 中华泌尿外科杂志, 2017, 38(10): 751-754. doi: 10.3760/cma.j.issn.1000-6702.2017.10.008
[9] Gerig N, Cameron T, Arora S, et al. Do we need more patient-friendly treatment options for overactive bladder(OAB)?[J]. Neurourol Urodyn, 2021, 40(6): 1433-1440. doi: 10.1002/nau.24731
[10] 石晓志, 乔西民, 徐晓峰, 等. 难治性膀胱过度活动症的治疗装置和技术的最新进展[J]. 中国医疗设备, 2018, 33(8): 111-114. doi: 10.3969/j.issn.1674-1633.2018.08.028
[11] Okhunov Z, Mao R, Jefferson FA, et al. Initial Evaluation of a Novel Modulated Radiofrequency-based Bladder Denervation Device[J]. Urology, 2019, 134: 237-242. doi: 10.1016/j.urology.2019.08.046
[12] Morady F. Radio-frequency ablation as treatment for cardiac arrhythmias[J]. N Engl J Med, 1999, 340(7): 534-544. doi: 10.1056/NEJM199902183400707
[13] Fugett J 2nd, Phillips L, Tobin E, et al. Selective bladder denervation for overactive bladder(OAB)syndrome: From concept to healing outcomes using the ovine model[J]. Neurourol Urodyn, 2018, 37(7): 2097-2105. doi: 10.1002/nau.23560
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