穿刺针数及穿刺位置对肾肿瘤穿刺活检影响的体外研究

陈松茂; 叶烈夫; 洪运; 胡敏雄

doi:10.13201/j.issn.1001-1420.2017.09.015

穿刺针数及穿刺位置对肾肿瘤穿刺活检影响的体外研究

- 1 福建省立金山医院泌尿外科(福州, 350000);
- 2 福建省立医院泌尿外科
基金项目:
2015年福建省卫生系统中青年骨干人才培养项目（编号2015-ZQN-ZD-1）

详细信息

通讯作者: 叶烈夫,E-mail:yeliefu@126.com

中图分类号: R737.11

收稿日期: 2016-06-20

Influence of puncture position and number of core on diagnostic accuracy of renal mass biopsy: an ex vivo study

- 1 Department of Urology, Fujian Jinshan Provincial Hospital, Fuzhou, 350000, China;
- 2 Department of Urology, Fujian Provincial Hospital

More Information

Corresponding author: YE Liefu, E-mail: yeliefu@126.com

Received Date: 20 June 2016

摘要

摘要: 目的：分析穿刺部位和穿刺针数不同对肾肿瘤穿刺病理诊断的影响。方法：2012年7月~2013年10月使用活检穿刺枪对52例术后切除的肾脏标本行穿刺术，中心区1针，周边区2针。穿刺标本制成病理切片，送病理医师观察并做出诊断。结果：收集标本52例，男30例（57.7%），女22例（42.3%），平均年龄54.9 （36~79）岁，肿瘤最大径平均值4.8 （2~15）cm。单取肿瘤中心区1针的穿刺成功率为90.4%，取肿瘤中心区与肿瘤周边区2针的穿刺成功率为98.1%，取材中心区与周边区共3针的穿刺成功率为100%。三种取材方式的成功率比较，1针比2针（P=0.035），2针比3针（P=0.201），1针比3针（P=0.007），α=0.0125，穿刺1针与3针存在差异。分别对比在肿瘤中心区与周边区穿刺所获取合格标本的成功率的差异（P=0.22）、肿瘤良恶性诊断的差异（P=1）和肾癌分型诊断的差异（P=0.25）均无统计学意义。结论：肾肿瘤穿刺针数越多，取材的成功率越高，取材3针的成功率可达到100%。在肾肿瘤的不同位置（中心区或周边区）穿刺取材对病理诊断结果的诊断准确性没有影响。
- 肾肿瘤 /
- 穿刺 /
- 针数 /
- 位置
Abstract: Objective: To evaluate whether renal mass biopsy (RMB) position or number of core affect diagnostic accuracy in an ex vivo study.Method: Three cores (one central and two peripheral) were obtained for histologic processing from each of 52 renal masses after nephrectomy from July 2012 to October 2013.Individual biopsy cores were evaluated independently for tumor subtype and grade by a single, blinded GU pathologist.Result: Renal masses were collected from 52 patients (30 males and 22 females) and the mean tumor size was 4.8 (range, 2-15) cm.Qualified tissues of central core were 90.4% of samples, and increased to 98.1% by adding peripheral a core, and to 100% with three cores.There is no diffence between one core and two cores to obtain qualified tissues (P=0.035).There was also no diffence between two cores and three cores (P=0.201).However, there was diffence between one core and three cores (P=0.007).There was no difference between cores from the center site or the peripheral site in obtainning eligible specimens (P=0.22) and diagnostic accuracy of benign or malignant (P=1) and accuracy of cancer subtyping (P=0.25).Conclusion: The more croes were obtained from puncture, the more eligible specimens were obtained.There is no difference between cores from the center site and the peripheral site.
- kidney neoplasms /
- biopsy /
- number of cores /
- position

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